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N/A N=51 Randomized Treatment

Efficacy of Social Cognition Training in Schizophrenia

Schizophrenia

Enrolled (actual)
51
Serious AEs
2.9%
Results posted
Oct 2025
Primary outcome: Primary: Social Cognitive Measures — 0.11; -1.68 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Social Cognition Interaction Training (Behavioral); WLC (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
VA Connecticut Healthcare System
Primary completion
Dec 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Social Cognitive Measures
0.11; -1.68
SECONDARY
Basic Cognitive Measures
1.61; 0.81

Summary

The term social cognition refers to how social information is processed. Individuals with schizophrenia and schizoaffective disorder have been shown to have significant deficits in social cognition. Moreover, it has been speculated that these deficits may in turn have a negative impact on their overall functioning. Behavioral interventions targeting social cognition are just beginning to emerge, and there is a need to evaluate their efficacy. Objectives: This is a small trial evaluating the efficacy of social cognition interaction training (SCIT) an experimental behavioral treatment for improving social cognition in schizophrenia. Research Design and Methodology: Approximately 48 participants with schizophrenia-spectrum disorders will be randomized into one of two conditions: 1) a 20 to 24 session manualized social cognition interaction training group (SCIT), or 2) wait-list control. Pre-and post-group therapy assessments of symptoms, social cognition, basic cognition, and community function will be conducted. Data obtained from this study will allow us to determine the efficacy of SCIT training in improving symptom, cognitive, and functional measures.

Eligibility Criteria

Inclusion Criteria

  • diagnosis of schizophrenia or schizoaffective disorder
  • Age between 18 and 65
  • minimum of 30 days since discharge from last hospitalization
  • minimum of 30 days since last change in psychiatric medications
  • no housing changes in the past 30 days

Exclusion Criteria

  • current diagnosis of alcohol or substance abuse/dependence
  • history of brain trauma or neurological disease
  • mental retardation or developmental disability
  • auditory or visual impairment that would interfere with study procedures
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00587561). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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