Phase 1 N=11 Randomized Treatment

Treatment of Language and Memory in Patients With Alzheimer's Disease

Alzheimer Disease

Bottom Line

View on ClinicalTrials.gov: NCT00593372 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2010

Primary outcome: Primary: Number of Successful Memory Tasks Completed Over Study Period. — 5; 0 memory tasks

Study Design & Population

Study type: Interventional
Phase: Phase 1
Interventions: Spaced Retrieval Training (Behavioral)
Age: Adult, Older Adult · 21+ yrs
Sex: All
Sponsor: University of Arkansas
Primary completion: Apr 2010

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Successful Memory Tasks Completed Over Study Period.	5; 0	—
SECONDARY Change on Mini-Mental State Examination	—	—

Summary

The purpose of this study is to collect data on the effects of behavioral interventions for memory and communication deficits in persons taking cholinesterase inhibitors compared with the effects of cholinesterase inhibitors alone. Initial testing will include a written case history, tests of communication skills, and interviews with the participants, family, and staff caregivers to help select potential goals for treatment. Participants will be randomly selected to participate in Group A (control) or Group B (intervention). Group A will use a Caregiver Checklist for eight weeks to identify any increase or decrease in the occurrence of the identified communication deficits. Group B will have 16 treatment sessions by a Speech Language Pathologist during the eight-week period. A post test will be administered to all participants.

Eligibility Criteria

Inclusion Criteria

Alzheimer's Disease (middle stage)

Exclusion Criteria

None

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00593372). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.