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Phase 2 N=6 Treatment

Study of Intranasal Clonazepam in Adult Subjects With Epileptic Seizures

Epilepsy

Enrolled (actual)
6
Serious AEs
0.0%
Results posted
Jul 2014
Primary outcome: Primary: Number of Spikes and Sharp Waves, Relative Change From Baseline to Treatment Day (%). — -7.4; -26.1 percentage of baseline

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
Clonazepam (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Jazz Pharmaceuticals
Primary completion
Dec 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Spikes and Sharp Waves, Relative Change From Baseline to Treatment Day (%).
-7.4; -26.1

Summary

Evaluate the safety and efficacy of intranasal Clonazepam in subjects with epilepsy.

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of refractory epilepsy
  • No Nasal conditions that would preclude the use of intranasal product

Exclusion Criteria

  • Subject with a clinical significant unstable medical abnormality
  • Subject currently or regularly taking Clonazepam
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00594945). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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