Optical genome mapping identifies mosaic structural variants in surgically resected epilepsy brain tissue
New mapping tool finds hidden genetic changes in epilepsy
This case series evaluates the utility of optical genome mapping (OGM) in detecting somatic structural variants in patients with epilepsy an…
A new way to map the genome is uncovering complex genetic mutations in brain tissue that standard testing often misses.
Bumetanide shows individual-level improvement in heterogeneous neurodevelopmental cohort
Bumetanide helps mood and sleep in kids with sensory issues.
In a post-trial access study using a multiple-baseline single-case experimental design, 113 youth (7–19 years) with ASD, ADHD, epilepsy, or …
Kids with autism, ADHD, or epilepsy who feel sensory overload saw better mood and sleep after taking bumetanide.
Predictive nomogram identifies suboptimal valproate concentrations in pediatric epilepsy patients using daily dose, organ injury, and meropenem.
New tool predicts dangerous valproate levels in children with epilepsy
This retrospective cohort study of 121 pediatric patients with epilepsy aged 2–18 years developed a predictive nomogram to identify suboptim…
A new calculator can flag children with epilepsy who are likely to get unsafe valproate levels, helping doctors adjust doses before problems…
Systematic Review Examines Cardiovascular Biomarkers for Pediatric Epilepsy Seizure Anticipation
Seizures May Be Predicted Before They Start
This systematic review evaluates non-invasive physiologic biomarkers, specifically cardiovascular electrocardiogram measurements, for seizur…
Every parent of a child with epilepsy knows the fear.
Atypical absences linked to higher autistic behavior scores in SYNGAP1-DEE patients
Seizure Type Predicts Autism Severity Better Than Frequency Does
This observational cohort study of 337 patients with SYNGAP1-related developmental and epileptic encephalopathy found that atypical absences…
For children with this rare condition, the kind of seizure matters more for autism symptoms than how often they occur.
Systematic review finds levetiracetam linked to psychobehavioral adverse effects in epilepsy
Levetiracetam linked to irritability and aggression in epilepsy patients
This systematic review synthesizes evidence on psychobehavioral adverse effects (PBAEs) of levetiracetam in epilepsy. It reports mean rates …
A review finds levetiracetam for epilepsy is tied to higher rates of irritability and aggression, with some patients stopping the drug becau…
Early-phase abstract reports closed-loop subgaleal stimulation safety and seizure reduction in epilepsy patients.
Short-pulse brain stimulation cut seizures by up to 83% in early epilepsy trials.
This first-in-patient study abstract describes closed-loop, subgaleal intersectional short-pulse stimulation for epilepsy. During the first …
In a first-in-patient study, a new brain stimulation method reduced seizure frequency by 83% and duration by 53% during the first three days…
Diagnostic accuracy study of EEG network measures for epilepsy versus functional seizures.
EEG Network Measures May Help Distinguish Epilepsy From Functional Seizures
This diagnostic accuracy study evaluated multivariate resting-state EEG network measures in 148 individuals with suspected seizure disorders…
EEG network measures can distinguish epilepsy from functional seizures with 67.5% accuracy, offering a new tool to help doctors diagnose sei…
Survey of epilepsy nurse training base construction needs across 29 Chinese provinces
Why Epilepsy Nurses Are the Missing Piece in Seizure Care
This cross-sectional survey assessed construction needs indicators for establishing epilepsy nurse training bases among 269 medical institut…
Doctors get the headlines, but for people living with epilepsy, the nurse who answers your 2 a.m. question may be the one who keeps life on …
AI approaches show potential for mapping brain-heart network interactions in neurocardiology
Can AI help us understand the hidden conversation between our brain and heart?
A systematic review explores artificial intelligence approaches for mapping and predicting brain-heart network dynamics across conditions li…
Artificial intelligence may decode the silent conversation between your brain and heart to spot hidden patterns in conditions like heart fai…
Meta-analysis finds pediatric epilepsy associated with multidimensional sleep architecture abnormalities
Children with epilepsy show more sleep problems than healthy peers, review finds
A systematic review and meta-analysis of 24 studies in pediatric populations with epilepsy found significantly higher sleep disturbance scor…
Children with epilepsy face more sleep problems than healthy peers, including less efficient rest and lower REM sleep vital for learning.
Report Compares Health Care Access for US Adults With and Without Epilepsy
Study examines health care access for US adults with epilepsy compared to those without
An observational report describes health care access among US adults aged ≥18 years with epilepsy compared to those without the condition. T…
A new report compares health care access for US adults with epilepsy to those without the condition.