N/A
Completed N=4,231
Circulation Improving Resuscitation Care (CIRC)
Cardiac Arrest · Cardiopulmonary Resuscitation
Source: ClinicalTrials.gov NCT00597207 ↗
Enrolled (actual)
4,231
Serious AEs
0.3%
Results posted
Apr 2014
Primary outcomePrimary: Hospital Discharge — 196; 233 participants
Summary
During resuscitation of out of hospital cardiac arrest patients the use of a mechanical chest compression device Autopulse will improve survival compared to manual compressions.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Hospital Discharge |
196; 233 | — |
Eligibility Criteria
Inclusion Criteria
- Patents aged 18 years (or local age of consent) or more who suffer non-traumatic arrest of presumed cardiac etiology in an out-of-hospital setting and who do not meet any of the exclusion criteria below.
Exclusion Criteria
- Traumatic arrest (blunt, penetrating, burns)
- Arrest due to exsanguinations, strangulation, smoke inhalation, drug overdose, electrocution, hanging, drowning.
- Known or clinically apparent pregnancy
- Do Not Attempt to Resuscitate (DNAR) orders
- Apparent patient weight more than 225 kg (500 lbs)
- Wards of the state
- Prisoner
- CPR device other than AutoPulse
- Patients who are reached after 16 minutes after the time of emergency call (911). This exclusion is determined at the time of CRF abstraction, not during treatment of the patient.
- If patient is unaccompanied, or accompanied by a person or persons unfamiliar with their his-tory, determination of these exclusion criteria will, perforce, be left to the best estimation of the rescue personnel. At no time, should an attempt to determine these criteria be allowed to delay the administration of life-saving treatment.
- These criteria will be determined in the best estimation of the rescue personnel, or if the AutoPulse signals that the patient is outside the parameters for AutoPulse deployment.
Data sourced from ClinicalTrials.gov (NCT00597207). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.