N/A N=21 Basic Science

Effect of Olopatadine on Allergic Tear Mediators

Allergic Conjunctivitis

Bottom Line

View on ClinicalTrials.gov: NCT00609128 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2018

Primary outcome: Primary: Study Examined Whether the Incubation of Human Conjunctival Epithelial Cells With Tears Pooled From Allergic Subjects (One Eye With and Other Eye Without Olopatadine Treatment) Promotes Eosinophil Adhesion — 4517; 5004 eosinophils/square cm epithelial cells — p=<0.05

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: olopatadine (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Wisconsin, Madison
Primary completion: Nov 2009

Outcome Measures

Outcome	Result	p-value
PRIMARY Study Examined Whether the Incubation of Human Conjunctival Epithelial Cells With Tears Pooled From Allergic Subjects (One Eye With and Other Eye Without Olopatadine Treatment) Promotes Eosinophil Adhesion	4517; 5004	<0.05 sig

Summary

The purpose of the research is to determine which inflammatory substances are involved in causing allergic symptoms in the eye. Allergic conjunctivitis is a common problem with symptoms of temporary redness, itching, tearing, and swelling of the eyes. Substances released by cells in the affected tissues cause allergic reactions in the eye and elsewhere in the body.

Eligibility Criteria

Inclusion Criteria

Skin test positive
Able to put drops in eyes
Able to have tears collected

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00609128). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.