N/A
Completed N=21
Effect of Olopatadine on Allergic Tear Mediators
Source: ClinicalTrials.gov NCT00609128 ↗Enrolled (actual)
21
Serious AEs
0.0%
Results posted
Sep 2018
Primary outcomePrimary: Study Examined Whether the Incubation of Human Conjunctival Epithelial Cells With Tears Pooled From Allergic Subjects (One Eye With and Other Eye Without Olopatadine Treatment) Promotes Eosinophil Adhesion — 4517; 5004 eosinophils/square cm epithelial cells — p=<0.05
Summary
The purpose of the research is to determine which inflammatory substances are involved in causing allergic symptoms in the eye. Allergic conjunctivitis is a common problem with symptoms of temporary redness, itching, tearing, and swelling of the eyes. Substances released by cells in the affected tissues cause allergic reactions in the eye and elsewhere in the body.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Study Examined Whether the Incubation of Human Conjunctival Epithelial Cells With Tears Pooled From Allergic Subjects (One Eye With and Other Eye Without Olopatadine Treatment) Promotes Eosinophil Adhesion |
4517; 5004 | <0.05 sig |
Eligibility Criteria
Inclusion Criteria
- Skin test positive
- Able to put drops in eyes
- Able to have tears collected
Data sourced from ClinicalTrials.gov (NCT00609128). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.