N/A N=13 Randomized Single-blind Treatment

The Efficacy of Hand Narrow-Band Ultraviolet B (NBUVB) Versus Excilite Treatment in Vitiligo After Minigrafting on the Dorsal Hands

Vitiligo

Bottom Line

View on ClinicalTrials.gov: NCT00622180 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2019

Primary outcome: Primary: Percent Repigmentation of Target Lesion — 0.21; 0.17 percentage of repigmentation

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: NBUVB (Device); Monochromacitc Excimer light (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Texas Southwestern Medical Center
Primary completion: Mar 2009

Outcome Measures

Outcome	Result	p-value
PRIMARY Percent Repigmentation of Target Lesion	0.21; 0.17	—

Summary

To assess over a 25-week period the efficacy of hand-foot narrow-band ultraviolet B light versus focal 308-nm light treatment in inducing the return of pigment in vitiligo after skin minigraft transplants to the backs of the hands in patients with light brown to black skin. Subject will undergo treatment for 13 weeks.

Eligibility Criteria

Inclusion Criteria

male and female subjects 18 years of age or older
skin type III-VI
vitiligo on both dorsal hands
history of stable vitiligo ( no new lesions and no more than 10% enlargement of existing lesions) for six months with an absence of Kebner phenomenon (new lesions appearing after trauma to the skin)
refractory to topical steroids and immunomodulators

Exclusion Criteria

pregnant and/or breast-feeding females
history of skin cancer
history of taking photosensitizing medications
history of recent phototherapy (light therapy) or topical medications within one month prior to enrollment
history of organ transplantation
history of failed vitiligo skin transplantation
history of segmental vitiligo
history of 12 or more continuous light treatments

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00622180). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.