N/A
Completed N=58,303
Long-term Active Surveillance Study for Oral Contraceptives (LASS)
Arterial Thromboembolism · Venous Thromboembolism · Breast Cancer
Source: ClinicalTrials.gov NCT00676065 ↗
Enrolled (actual)
58,303
Serious AEs
13.7%
Results posted
Nov 2014
Primary outcomePrimary: Arterial Thromboembolism — 7; 22; 34 participants
Summary
The objective of this study is to characterize and compare the risks of long-term use of oral contraceptives containing drospirenone and of other established oral contraceptives.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Arterial Thromboembolism |
7; 22; 34 | — |
| PRIMARY Venous Thromboembolism |
56; 53; 144 | — |
| PRIMARY Breast Cancer |
27; 31; 45 | — |
Eligibility Criteria
Inclusion Criteria
- Women who are prescribed an oral contraceptive and who are new users (first-ever users, switchers or restarters) of the formulation
Exclusion Criteria
- Women who do not consent to participate in the study
Data sourced from ClinicalTrials.gov (NCT00676065). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.