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N/A N=150 Randomized Quadruple-blind Treatment

Study of Intramuscular Ropivacaine Injections for Treatment of Pediatric Headache

Headache · Migraine

Enrolled (actual)
150
Serious AEs
0.0%
Results posted
Dec 2017
Primary outcome: Primary: The Primary Outcome Will be Pain Relief Sufficient for Discharge From the Emergency Department. — 16; 14; 2 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Ropivacaine (Drug); Normal saline (Drug)
Age
Pediatric · 7+ yrs
Sex
All
Sponsor
Robert Hickey
Primary completion
Jun 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
The Primary Outcome Will be Pain Relief Sufficient for Discharge From the Emergency Department.
16; 14; 2
SECONDARY
Number and Percent of Patients Admitted to the Hospital for Additional Therapy in Each Treatment Arm Based Upon Treating Clinicians Decision
10; 10; 12
SECONDARY
Re-presentation to the Emergency Department With Headache Within 72 Hours of Participating in the Study
7; 7; 4

Summary

Objective: To determine if lower paracervical intramuscular ropivacaine injection is an effective treatment for pediatric headache in an emergency department setting.

Eligibility Criteria

Inclusion Criteria

  • Chief complaint of headache
  • Age 7-17 years

Exclusion Criteria

  • Presence of fever
  • meningismus
  • headache that wakes the child at night
  • known organic brain disease, mass, or tumor
  • history of stroke
  • history of allergy to ropivacaine or other aminoacyl local anesthetics
  • history of liver disease
  • history of impaired cardiac function
  • abnormal neurologic signs
  • a focal neurologic abnormality on exam that is not a known component of the child's headache syndrome
  • cognitive inability to communicate the intensity of pain.
  • history of shunt or other intracranial hardware
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00680823). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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