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Phase 4 N=25 Randomized Treatment

Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis

Atopic Dermatitis

Enrolled (actual)
25
Serious AEs
0.0%
Results posted
Mar 2017
Primary outcome: Primary: Adherence to Locoid — .55; .60; .50 percentage of days

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
hydrocortisone 17-butyrate 0.1% Cream preparation (Drug); hydrocortisone 17-butyrate 0.1% Ointment preparation (Drug); hydrocortisone 17-butyrate 0.1% Lipocream preparation (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Wake Forest University
Primary completion
Sep 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Adherence to Locoid
.55; .60; .50

Summary

The purpose of this research study is to better understand adherence to Locoid when people use it to treat atopic dermatitis.

Eligibility Criteria

Inclusion Criteria

  • Male or female ≥ 18 years of age.
  • Subjects must have diagnosis of mild to moderate atopic dermatitis using IGA criteria. (2 or 3 on severity scale)
  • Subjects must have >5% TBSA and 130 gm of cream in a 2 week period.
  • Having facial or groin involvement of their disease.
  • Pregnant women and women who are breast feeding are to be excluded. Women of child bearing potential will be allowed to participate in the study, and these subjects will be required to use at least one form of birth control.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00693693). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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