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Atopic Dermatitis

Part of Dermatitis

29 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Atopic Dermatitis

250 trials tracked for Atopic Dermatitis: 104 in phase 3 or 4 and 58 with published results. The most-cited published study has 2038 citations.

250Trials tracked
104Phase 3 & 4
0Recruiting
58With published results
Phase distribution
Phase 4 28 Phase 3 76 Phase 2 115 Phase 1 11 Other / NA 20
  1. Phase 3 Study of Dupilumab (REGN668/SAR231893) Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis Completed · 2,038 cited
  2. Phase 3 Study of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis Completed · 2,034 cited
  3. Phase 3 A Study to Compare Safety and Efficacy of Upadacitinib to Dupilumab in Adult Participants With Moderate to Severe Atopic Dermatitis Completed · 479 cited
  4. Phase 3 Open-label Study of Dupilumab in Patients With Atopic Dermatitis Completed · 226 cited
  5. Phase 3 A Study to Confirm the Efficacy and Safety of Different Dupilumab Dose Regimens in Adults With Atopic Dermatitis (AD) Completed · 200 cited
  6. Phase 3 JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis Completed · 160 cited
Show 44 more trials
  1. Phase 3 Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis. Completed · 136 cited
  2. Phase 3 Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6). Completed · 134 cited
  3. Phase 3 Efficacy and Safety of Dupilumab in Participants ≥12 to <18 Years of Age, With Moderate-to-severe Atopic Dermatitis Completed · 117 cited
  4. Phase 4 Comparing Aquaphor to Atopiclair and EpiCeram in Children With Mild to Moderate Atopic Dermatitis Completed · 104 cited
  5. Phase 3 A Study of Long-term Baricitinib (LY3009104) Therapy in Atopic Dermatitis Completed · 96 cited
  6. Phase 4 A Study of Crisaborole Ointment 2% in Children Aged 3-24 Months With Mild to Moderate Atopic Dermatitis Completed · 89 cited
  7. Phase 3 Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102) Completed · 83 cited
  8. Phase 3 Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis Completed · 82 cited
  9. Phase 3 Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults Completed · 82 cited
  10. Phase 3 Comparison Trial of OPA-15406 Ointment in Pediatric Patients With Atopic Dermatitis Completed · 65 cited
  11. Phase 3 A Study of Baricitinib (LY3009104) in Adult Participants With Moderate to Severe Atopic Dermatitis Completed · 56 cited
  12. Phase 3 A Study to Assess the Efficacy and Safety of Dupilumab in Participants With Severe Atopic Dermatitis (AD) That Are Not Controlled With Oral Cyclosporine A (CSA) or for Those Who Cannot Take Oral CSA Because it is Not Medically Advisable Completed · 54 cited
  13. Phase 3 Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 1 (ECZema TRAlokinumab Trial no. 1) Completed · 53 cited
  14. Phase 3 Tralokinumab in Combination With Topical Corticosteroids for Moderate to Severe Atopic Dermatitis - ECZTRA 3 Completed · 49 cited
  15. Phase 3 Long-term Extension Trial in Subjects With Atopic Dermatitis Who Participated in Previous Tralokinumab Trials - ECZTEND Completed · 49 cited
  16. Phase 3 A Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis Completed · 43 cited
  17. Phase 3 Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis Completed · 43 cited
  18. Phase 3 A Study of Baricitinib (LY3009104) in Combination With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis Completed · 43 cited
  19. Phase 3 A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled With Cyclosporine or for Those Who Cannot Take Oral Cyclosporine Because it is Not Medically Advisable Completed · 43 cited
  20. Phase 3 Study to Assess the Safety and Efficacy of Lebrikizumab (LY3650150) in Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Completed · 41 cited
  21. Phase 3 A Study to Evaluate Long-Term Maintenance Treatment With Once Daily Crisaborole Ointment 2% in Pediatric and Adult Participants With Mild-to-Moderate Atopic Dermatitis Completed · 41 cited
  22. Phase 3 Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticosteroids (TCS) in Participants ≥6 to <12 Years With Severe Atopic Dermatitis (AD) Completed · 37 cited
  23. Phase 3 Efficacy and Safety of a Retinoid in the Treatment of Severe Chronic Hand Eczema Completed · 33 cited
  24. Phase 3 Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 2 (ECZema TRAlokinumab Trial no. 2) Completed · 29 cited
  25. Phase 3 Evaluation of Dupilumab in Chinese Adult Patients With Moderate to Severe Atopic Dermatitis Completed · 26 cited
  26. Phase 3 Topical Ruxolitinib Evaluation in Atopic Dermatitis Study 1 (TRuE AD1) - An Efficacy and Safety Study of Ruxolitinib Cream in Adolescents and Adults With Atopic Dermatitis Completed · 23 cited
  27. Phase 3 TRuE AD2 - An Efficacy and Safety Study of Ruxolitinib Cream in Adolescents and Adults With Atopic Dermatitis Completed · 23 cited
  28. Phase 3 Long-term Trial of OPA-15406 Ointment in Adult and Pediatric Patients With Atopic Dermatitis Completed · 22 cited
  29. Phase 3 Safety and Efficacy of AN2728 Topical Ointment, 2% in Children, Adolescents, and Adults (Aged 2 Years and Older) With Atopic Dermatitis Completed · 19 cited
  30. Phase 3 Safety and Efficacy of AN2728 Topical Ointment, 2% in Children, Adolescents, and Adults (Ages 2 Years and Older) With Atopic Dermatitis Completed · 19 cited
  31. Phase 3 Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema) Completed · 15 cited
  32. Phase 3 A Study to Evaluate Upadacitinib in Adolescents and Adults With Moderate to Severe Atopic Dermatitis (Measure Up 2) Completed · 15 cited
  33. Phase 3 Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects Completed · 12 cited
  34. Phase 3 Study Evaluating Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis Completed · 12 cited
  35. Phase 3 Study to Evaluate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis Completed · 12 cited
  36. Phase 3 Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis Completed · 11 cited
  37. Phase 3 Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1) Completed · 11 cited
  38. Phase 3 A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children With Atopic Dermatitis (TRuE-AD3) Completed · 11 cited
  39. Phase 3 Safety, Pharmacokinetics and Efficacy of Dupilumab in Patients ≥6 Months to <6 Years With Moderate-to-Severe Atopic Dermatitis (Liberty AD PRESCHOOL) Completed · 10 cited
  40. Phase 3 Study of Abrocitinib Compared With Dupilumab in Adults With Moderate to Severe Atopic Dermatitis on Background Topical Therapy Completed · 10 cited
  41. Phase 3 A Study of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroids in Japanese Participants With Moderate-to-Severe Atopic Dermatitis Completed · 7 cited
  42. Phase 3 A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color Completed · 6 cited
  43. Phase 3 Long-term Safety and Efficacy Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis (ADjoin) Completed · 5 cited
  44. Phase 3 Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy Completed · 3 cited

Showing the 50 most-cited and recently-updated of 250 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Dermatitis

Related studies from across the Dermatitis family.

1 514 781 patients shows methylisothiazolinone allergy prevalence is 5.48% in dermatitis cases
Allergy & Immunology Meta-analysis
1 514 781 patients shows methylisothiazolinone allergy prevalence is 5.48% in dermatitis cases Large review shows contact allergy to isothiazolinones affects many dermatitis patients
This systematic review and meta-analysis examined contact allergy prevalence to isothiazolinones in 1 514 781 dermatitis patients from 2000 …
A massive review of over 1.5 million patients found that contact allergy to isothiazolinones is common in dermatitis cases, with methylisoth…
Review highlights emerging mechanisms for allergic contact dermatitis management
Dermatology Sys. Review
Review highlights emerging mechanisms for allergic contact dermatitis management Critical gaps remain in understanding allergic contact dermatitis sensitization thresholds
This narrative review discusses allergic contact dermatitis and notes critical gaps persist regarding tissue-resident memory T cells and pre…
A review of allergic contact dermatitis highlights emerging mechanisms that may support the development of more precise and effective therap…
Narrative review discusses ginsenosides for skin conditions including psoriasis and dermatitis with noted evidence gaps
Drug Pipeline Sys. Review
Narrative review discusses ginsenosides for skin conditions including psoriasis and dermatitis with noted evidence gaps Review of ginsenosides for skin conditions shows weak evidence and low absorption
This narrative review examines the use of ginsenosides for various skin conditions, including psoriasis, dermatitis, photoaging, chronic non…
A review of ginsenosides for skin issues like psoriasis and melanoma found the evidence is insufficient and absorption is low.

Questions about Atopic Dermatitis

Does swimming pool attendance increase asthma risk in children with atopic dermatitis?

Swimming pool attendance is linked to a small increase in asthma risk in children, but no clear link to atopic dermatitis itself.

Full answer →
What is the national prevalence of atopic dermatitis in Ethiopia?

The national prevalence of atopic dermatitis in Ethiopia is approximately 12.75%, based on a systematic review and meta-analysis of 10 studies with 25,920 participants.

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Is dupilumab an effective treatment for pediatric atopic dermatitis?

Yes, dupilumab is an effective treatment for pediatric atopic dermatitis, with clinical trials showing significant improvement in skin clearance and itch reduction in children as young as 6 months.

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Does Staphylococcus aureus colonization make my atopic dermatitis worse?

Yes, Staphylococcus aureus colonization is moderately linked to worse atopic dermatitis severity, though this does not prove direct causation.

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All Atopic Dermatitis Articles