N/A
N=99
hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects
Healthy Subjects · Vitamin D Deficiency
Bottom Line
View on ClinicalTrials.gov: NCT00742235 ↗Enrolled (actual)
99
Serious AEs
0.0%
Results posted
Nov 2013
Primary outcome: Primary: hCAP18 Levels — 762; 639 ng/ml
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- ergocalciferol (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Massachusetts General Hospital
- Primary completion
- Jan 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY hCAP18 Levels |
762; 639 | — |
| PRIMARY Baseline 25-OH Vitamin D Level |
40; 25 | — |
Summary
Vitamin D deficiency (low levels of vitamin D in the blood) is a common problem. A recently discovered protein, called hCAP18, likely plays an important role in the immune system and may depend on adequate levels of vitamin D. It is not known what levels of vitamin D are needed to allow the body to make this protein. Nor is it known if giving vitamin D to people who are found to be deficient will help boost levels of hCAP18. This study aims to clarify the relationship between vitamin D levels and hCAP18.
Eligibility Criteria
Inclusion Criteria
- Age 18-80
Exclusion Criteria
- Known active infectious disease or chronic inflammatory disorder
- Hypercalcemia
- Chronic kidney disease
- Pregnancy
Data sourced from ClinicalTrials.gov (NCT00742235). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.