N/A N=73 Randomized Double-blind Prevention

Does Atorvastatin Prevent Post Operative Atrial Fibrillation After Pulmonary Resection: A Randomized Clinical Study

Arrhythmia

Bottom Line

View on ClinicalTrials.gov: NCT00756886 ↗

Enrolled (actual)

Serious AEs

25.5%

Results posted

Apr 2013

Primary outcome: Primary: Atrial Fibrillation — 6; 1 participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Atorvastatin (Drug); Placebo (Drug)
Age: Adult, Older Adult · 19+ yrs
Sex: All
Sponsor: University of Alabama at Birmingham
Primary completion: May 2011

Outcome Measures

Outcome	Result	p-value
PRIMARY Atrial Fibrillation	6; 1	—

Summary

The purpose of this study is to determine if atorvastatin (Lipitor) reduces the occurence of abnormal heart rhythm (atrial arrhythmia) following non cardiac thoracic surgery.

Eligibility Criteria

Inclusion Criteria

Patients scheduled for elective non-cardiac thoracic surgery requiring thoracotomy for resection

Exclusion Criteria

Past medical history of pacemaker implantation
Pregnancy or lactating
History of Atrial arrhythmia within the past year
Elevated liver enzymes pre-operatively
Past medical history of any liver disease or history of liver transplantation
Use of statins or any anti-arrhythmics (including beta-blockers, calcium channel blockers, digoxin) within 3 months prior to surgery
Pre-op EKG showing atrial arrhythmia

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00756886). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.