N/A N=19 Single-blind Basic Science

Endothelial Function in Lower Extremity Bypass Grafts

Peripheral Arterial Disease

Bottom Line

View on ClinicalTrials.gov: NCT00759707 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2017

Primary outcome: Primary: Change From Baseline in Saphenous Vein Bypass Graft Vasodilation — 5.28 vein bypass graft size increase (%)

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: L-N^G monomethyl arginine (L-NMMA) (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Brigham and Women's Hospital
Primary completion: Dec 2009

Outcome Measures

Outcome	Result	p-value
PRIMARY Change From Baseline in Saphenous Vein Bypass Graft Vasodilation	5.28	—

Summary

This study will determine whether or not saphenous vein [arterial] bypass grafts in the leg relax in response to increases in blood flow.

Eligibility Criteria

Inclusion Criteria

Adults who have undergone femoral artery to above-knee popliteal artery saphenous vein bypass grafts

Exclusion Criteria

Amputation beyond the toes
Critical limb ischemia defined as rest pain, non-healing ulceration or gangrene
Pregnancy

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00759707). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.