A Study to Compare the NexGen LPS and LPS-Flex Knee Implants

Inclusion Criteria

• Age, 21-80 years
• Sex, Males and females will be included
• BMI less than or equal to 39 and calf-thigh less than or equal to 90 degrees
• Stable health, the patient would be able to undergo surgery and participate in the follow-up program based on physical examination and medical history.
• Patient is willing and able to cooperate in follow-up therapy.
• Patient exhibits preoperative radiographic evidence of joint degeneration consistent with TKA that cannot be treated in non-operative fashion.
• Patient has stable and functional collateral ligaments.
• Patient has potential to perform higher than average range of motion activities.
• Operative side range of motion flexion greater than or equal to 90 degrees.
• Severe knee pain and disability due to degenerative joint disease.
• Patient or patient's legal representative has signed the Informed Consent form.

Exclusion Criteria

• Previous history of infection in the affected joint.
• Previously failed knee endoprosthesis of any kind.
• Charcot joint disease or other severe neurosensory deficits.
• Previous patellectomy.
• Patient is skeletally immature.
• Grossly insufficient femoral or tibial bone stock.
• Patient is pregnant.
• Varus or valgus deformity greater than 20 degrees.
• Fixed flexion deformity greater than 15 degrees.
• Previous high tibial osteotomy.
• Previous femoral osteotomy.
• Patient is a poor compliance risk - currently treated for ethanol or drug abuse, physical or mental handicap, etc.
• Loss of musculature or absence of musculoligamentous supporting structures required for adequate soft tissue balance.