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N/A N=851

Study Comparing Remission Rates, in Patients With Major Depressive Disorder (MDD)

Major Depressive Disorder

Enrolled (actual)
851
Serious AEs
Results posted
Aug 2012
Primary outcome: Primary: Percentage of Participants With Remission Based on Hamilton Depression Scale (HAM-D) — 54.4 Percentage of participants

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Cohort (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Pfizer
Primary completion
Dec 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
Percentage of Participants With Remission Based on Hamilton Depression Scale (HAM-D)
54.4
SECONDARY
Percentage of Participants With Remission Based on Beck Depression Inventory (BDI)
64.6
SECONDARY
Hamilton Depression Scale 17 (HAM-D17), HAM-D7 and Beck Depression Inventory (BDI)
25.18; 13.53; 31.45; 7.31; 4.07; 9.03 <0.0001 sig
SECONDARY
Number of Participants With Residual Symptoms in Case of Non Remission
59; 35; 22; 22; 20; 4

Summary

Tools known as 'depression scales 'are widely used as assessments to evaluate a patient's response to treatment. The purpose of this study is the evaluation of the remission rates for patients with MDD. The evaluation will involve the use of HAM-D 17, and HAM-D 7 questionnaires and the comparison of those questionnaires.

Eligibility Criteria

Inclusion Criteria

  • Outpatients
  • 18-75 years old
  • Patients diagnosed with MDD according to DSM IV without psychotic symptoms
  • HAM-D17 > or = 18 on inclusion
  • Patients receiving treatment for the first time or changing treatment based on their doctor's decision

Exclusion Criteria

  • Subjects with potentially problematic compliance
  • Subjects participating in an interventional trial within the last 3 months
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00770289). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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