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Phase 3 N=2,031 Randomized Triple-blind Health Services Research

HIV Testing & Womens Attitudes on HIV Vaccine Trials

HIV

Enrolled (actual)
2,031
Serious AEs
Results posted
Jul 2013
Primary outcome: Primary: Number of Participants Who Accepted Rapid HIV Testing. — 458; 401; 410; 418 participants — p=0.05

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Message Sidedness (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Indiana University
Primary completion
Jan 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants Who Accepted Rapid HIV Testing.
458; 401; 410; 418 0.05
PRIMARY
Willingness to Participate in a HIV Vaccine Clinical Trial
2.46; 2.52; 2.55; 2.47 <.60

Summary

The purpose of this study is to test the effects of different persuasive informational messages on rates of rapid HIV testing and willingness to participate in a HIV vaccine clinical trial. Adult African-American, non-Latina White, and Latina women will be recruited. Women will initially be randomized to 4 groups: 1. no message control; 2. 1-sided message that mentions benefits of HIV testing; 3. 2-sided message that acknowledges minor opposition to testing, then refutes the opposition; and 4. 2-sided message that acknowledge stronger opposition to testing, then refutes the opposition. Women will be offered HIV testing, then re-randomized to a similar set of 4 messages related to HIV vaccine trials. There will therefore be 16 groups in total (4 X 4).

Eligibility Criteria

Inclusion Criteria

  • Female
  • 18 years of age or older
  • Able to understand English or Spanish
  • Able to give informed consent

Exclusion Criteria

  • Not female
  • Under 18 years of age
  • Not able to understand English and Spanish
  • Unable to give informed consent
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00771537). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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