Phase 4 N=27 Treatment

Strict Glycemic Control by Insulin Infusion:Observations on Emergency Department Initiation

Hyperglycemia

Bottom Line

View on ClinicalTrials.gov: NCT00779701 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2015

Primary outcome: Primary: Time to Achieve Glycemic Control — 225 Minutes

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: Insulin (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Temple University
Primary completion: Oct 2009

Outcome Measures

Outcome	Result	p-value
PRIMARY Time to Achieve Glycemic Control	225	—

Summary

Glycemic control can be safely achieved in surgical and medical intensive care unit settings and has been shown to improve short and long-term clinical outcomes. As such, insulin infusion protocols are routinely used in the ICU setting. The investigators plan to establish the use of strict glycemic control in a heterogenous group of acutely ill patients in the ED setting. The investigators propose to study the aspects of implementing a strict glycemic control protocol in the ED.

Eligibility Criteria

Inclusion Criteria

Patients with blood glucose ≥130 mg% considered to be critically ill as defined by:

APACHE II score ≥9 (See Appendix 1) OR >2 SIRS criteria with lactate ≥ 4 or BP < 90mmHg despite one liter of fluid OR Evidence of Organ Dysfunction (see Appendix 1)

Exclusion Criteria

Patients requiring urgent interventional procedure (e.g. cardiac catheterization, dialysis) or surgery performed outside of the ED.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00779701). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.