Phase 2 N=61 Randomized Quadruple-blind Treatment

Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial

Cervical Strain

Bottom Line

View on ClinicalTrials.gov: NCT00790270 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2012

Primary outcome: Primary: Pain

Study Design & Population

Study type: Interventional
Phase: Phase 2
Interventions: Cyclobenzaprine (Drug); Ibuprofen (Drug); Ibuprofen plus Cyclobenzaprine (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Stony Brook University
Primary completion: Jan 2004

Outcome Measures

Outcome	Result	p-value
PRIMARY Pain	—	—
PRIMARY Use of Rescue Medications	13; 9; 9	—
SECONDARY Time to Resumption of Work	—	—
SECONDARY Resumption of Work or School	8; 14; 13	—

Summary

The purpose of this study is to see whether the combination of a muscle relaxant and anti-inflammatory drug is more effective at relieving pain in patients with neck strains or whiplash than either of the two medications alone.

Eligibility Criteria

Inclusion Criteria

neck pain within 24 hours of injury

Exclusion Criteria

Children, allergy or contraindication to any of the study drugs

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00790270). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.