N/A N=30 Cervical Activation During Elastic and Manual Resistance
Cervical Pain
Primary: Percent of Peak Activation (%PA) — 51.72; 61.20; 88.1; 80.80 Percentage of Peak Activation (%PA)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=61 Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial
Cervical Strain
Primary: Pain
N/A N=60 Heat Versus Ice in the Acute Management of Neck and Back Strain Injuries
Back Strain · Neck Strain
Primary: Pain Score After Treatment — 66; 64 mm
Phase 2 N=10 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain
Neck Pain
Primary: Occiflex Device Safety — 26 Number of adverse effects
Phase 4 N=123 Study to Assess the Effectiveness and Safety of FLECTOR Patch for Treatment of Acute Back Strain
Acute Back Strain
Primary: Mean Change From Baseline to End of Treatment (EOT) in Response to Modified Brief Pain Inventory (mBPI) Question 5: Average Pain Over the Last 24 Hours — 6.46; -3.95…
N/A N=43 Benefit of Adding Stretching to Standard Intervention For Patients With Nonspecific Mechanical Neck Pain
Neck Pain
Primary: Cervical Range of Motion — 46.2; 46.1; 71.2; 68.5 Degree
N/A N=30 Clavicle Splint for Pain Reduction After Posterior Cervicothoracic Surgery
Posterior Cervical Surgery · Posterior Cervical Fusion · Posterior Cervical Laminectomy
Primary: Average Neck Pain Level — 1; 1 units on a scale (VAS pain scale)
N/A N=48 Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial
Neck Pain · Pain in Arm, Unspecified
Primary: Range of Traction Forces — 13.82; 38.3; 65.08; 17.19 Newtons (N)
N/A N=38 Measurements of Angulation of the C-spine
Cervical Spine
Primary: Measurements of Angulation of the Neck (C-spine) on MRI Scans — 10.6; 21.6; 5.5; 4.1 degrees — p=<0.001
Phase 3 N=180 Cyclobenzaprine HCl Extended Release 15 mg Versus Placebo in Treatment of Cervical and/or Lower Back Pain Due to Muscle Spasms of Local Origin
Neck Pain · Back Pain · Spasm
Primary: Percentage of Participants With Subject's Rating of Medication Helpfulness Impression on Day 3 of Treatment — 20.0; 28.9; 60.0; 46.7 percentage of participants — p=0.6179
N/A N=28 The Effect of Manipulation of the Cervical Spine on Pain Biomarkers
Neck Pain, Posterior
Primary: Plasma Concentration of Oxytocin — 154.5; 158.8 ug/ml
N/A N=98 Preventive Care of Chronic Cervical Pain and Disabilities
Neck Pain
Primary: Neck Pain — 3.8; 3.3; 3.4 cm
N/A N=8 Postural Stability in Cervical Spinal Myelopathy
Cervical Spondylotic Myelopathy
Primary: Virtual Environment TBI System (VETS) Assessment of Static Posturography — 11; 13.0; 48.4; 19.1 Square Centimeters
Phase 4 N=79 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain
Radicular; Neuropathic, Cervical · Neck Pain
Primary: Percentage of Participants With ≥50% Pain Reduction on the Numeric Rating Score (NRS) for Pain — 60; 72 percentage of participants — p=0.23
N/A N=20 Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
Vertebral Artery Dissection · Cerebrovascular Accident · Stroke
Primary: Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation — 15.5; 15.1; 14.7 cm/s
N/A N=19 Driving After Cervical Spine Surgery
Cervical Disc Disease
Primary: Change in Number of Total Collisions (TC) — 2 collisions/crashes
N/A N=43 How do the Neck Muscles Influence Head Acceleration During Sport-associated Impact Events in High School Athletes?
Sport-related Concussion · Brain Concussion · Healthy
Primary: Mean Area Under the Net Head Acceleration vs. Time Curve During Direct Loading, With Anticipatory Bracing - Linear Motion. — .895; 1.069; .873; .903 meters per second…
N/A N=4,034 Evaluation of the Safety of C-Spine Clearance by Paramedics
Fracture of Cervical Spine
Primary: Adverse Events — 1 Adverse event
N/A N=50 The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion
Acute Non-complicated Postural Neck Pain
Primary: Change in Cervical Range of Motion — 37.9; 36.9; 39.5; 37.5 degrees
N/A N=20 Dispersal Pattern for Spine Injections (Gadolinium Contrast)
Cervical Radiculopathy
Primary: Injection Dispersal Patterns Measured (in cm) in the Superoinferior Directions on Post-injection MRI With a Calibrated Internal Measurement Software. — 14.73 cm
Phase 4 N=123 CESI With Low Dose Lidocaine and Transient Weakness
Cervical Radiculitis · Pain
Primary: Change in Strength in Both Groups After CESI. — 25; 30; 35; 30 Participants — p=.05
N/A N=42 Quantifying Myofascial Dysfunction in Post-Stroke Pain
Myofascial Dysfunction
Primary: T1 Rho MRI Relaxation Time of Shoulder External Rotator (Milliseconds) — 29.09; 27.15 milliseconds
N/A N=104 Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Radiating Pain · Myelopathy · Cervicobrachial Syndrome
Primary: Neck Disability Index — 17.9; 16.7 units on a scale from 0 to 100 — p=0.641
Phase 2 N=242 Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia
Cervical Dystonia
Primary: Change From Baseline in Observed Total Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) Score at Week 4 of Treatment Cycle 1 — 40.4; 41.5; 39.6; -10.3 Scores…
N/A N=74 Dysphagia Following Anterior Cervical Spine Surgery; Steroid vs Saline
Dysphagia
Primary: Swallowing Difficulty — 16; 14; 5; 7 Participants — p=0.036
N/A N=231 Outcome Study of Patients Treated With Translational Cervical Plate Used to Treat Degenerative Disc Disease
Degenerative Disc Disease
Primary: Radiographic Fusion — 66; 46; 37; 75 percentage of subjects
N/A N=27 Evaluation of Comfort in a Spinal Collar
Neck Injuries
Primary: Measurement of the Level of Discomfort Produced by the Spinal Collar in Adult Patients With a C-spine (Neck) Injury. — 1; 4.9 score on a scale
Phase 4 N=65 Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain
Pain, Radiating
Primary: Avoidance of Neck Surgery — 24; 20; 3; 6 Participants
Phase 2 N=62 The Effectiveness of a Mechanical Manual Therapy Device in the Treatment of Neck Pain
Neck Pain
Primary: 2 Week Change in Pain Score on a Numeric Rating Scale — 6.39; 20.37; 6.45 units on a scale — p=0.10
N/A N=22,430 Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool
Cervical Spine Injury
Primary: Cervical Spine Injury — 274; 159 Participants — p=.05