N/A
N=100
Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena
Pharyngitis
Bottom Line
View on ClinicalTrials.gov: NCT00798018 ↗Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Dec 2009
Primary outcome: Primary: Visual Analogue Scale(0-100mm) by the Subject. — 51; 40; 22; 9 mm
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- 2% lidocaine (Drug); placebo (Drug); 1% tetracaine (Drug); N.S (Drug)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Sichuan University
- Primary completion
- Feb 2009
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Visual Analogue Scale(0-100mm) by the Subject. |
51; 40; 22; 9; 50; 38 | — |
Summary
It has been proven that tracheal tube inflated with lidocaine could decrease the post-intubation sore throat in nitrous oxide anesthesia. In the study, the investigators would like to evaluate the effect of lidocaine inflation in non-nitrous oxide anesthesia and compare the effect of tetracaine, the best mucosal local anesthetics with lidocaine.
Eligibility Criteria
Inclusion Criteria
- patients of the age group 18-60 years
- patients belonging to ASA grade I and II undergoing gynecological surgeries in supine position under general anesthesia with controlled ventilation using Poly Vinyl Chloride ETT (same type and make in all patients)
Exclusion Criteria
- anticipated difficult intubation
- more than one attempt for intubation
- need for naso gastric tube
- episode of coughing and straining
- history of respiratory tract infection and smoking
Data sourced from ClinicalTrials.gov (NCT00798018). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.