N/A
N=4,455
Study to Evaluate Impact of School-based Influenza Vaccination on School Populations
Influenza
Bottom Line
View on ClinicalTrials.gov: NCT00844051 ↗Enrolled (actual)
4,455
Serious AEs
0.0%
Results posted
Aug 2016
Primary outcome: Primary: Rates of Confirmed Influenza Illness in Vaccinated and Non-vaccinated Children Attending Schools With and Without School-based Influenza Vaccination Programs — 58.0; 40.1 flu+ per 1000 children
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- School-based influenza vaccination program (Biological)
- Age
- Pediatric, Adult · 4+ yrs
- Sex
- All
- Sponsor
- Children's Hospital Los Angeles
- Primary completion
- Jun 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Rates of Confirmed Influenza Illness in Vaccinated and Non-vaccinated Children Attending Schools With and Without School-based Influenza Vaccination Programs |
58.0; 40.1 | — |
| SECONDARY Rates of Absenteeism Among Children Attending Schools With and Without School-based Influenza Vaccination Programs |
4.2; 3.9 | — |
Summary
Rates of confirmed influenza illness in vaccinated and non-vaccinated children will be compared between schools with and without vaccination programs. The investigators hypothesize that in addition to lowering rates of influenza in vaccinated children, raising vaccination rates by 30-40% through school-based vaccination programs will decrease incidence of influenza in non-vaccinated children attending those schools compared to non-vaccinated children in schools with low vaccination rates.
Eligibility Criteria
Inclusion Criteria
- Children enrolled in target schools
Exclusion Criteria: none
Data sourced from ClinicalTrials.gov (NCT00844051). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.