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N/A N=58 Randomized Quadruple-blind Treatment

Mobility Optimization Through Velocity Exercise

Knee Osteoarthritis

Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Jun 2016
Primary outcome: Primary: Change in Basic Lower Limb Function (Late Life Function Index) Late Life Function and Disability Instrument — 3.3; -1.0; 3.1; 0.8 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Gait Training (Other); Control (Other)
Age
Adult, Older Adult · 60+ yrs
Sex
All
Sponsor
University of Iowa
Primary completion
Oct 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Basic Lower Limb Function (Late Life Function Index) Late Life Function and Disability Instrument
3.3; -1.0; 3.1; 0.8; 3.9; 2.9
SECONDARY
Change in Knee Osteoarthritis Injury and Outcome Scale (KOOS) Pain
8.2; 1.1; 5.4; 1.7; 10.1; 2.8
SECONDARY
Change in KOOS Symptoms
11.5; 3.0; 8.1; 1.8; 8.5; 2.4
SECONDARY
Change in Long Distance Corridor Walk (LDCW) Time, Secs
11.5; 3.0; 8.1; 1.8; 8.5; 2.4
SECONDARY
Change in Stair Climb Time, Secs
0.2; 0.0; -0.2; -1.4; -0.3; -1.1
SECONDARY
Change in Chair Stand Time
-0.9; -1.0; -1.9; -3.0; -2.5; -2.9

Summary

Knee Osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults. The purpose of this research is to reduce disablement of older adults with symptomatic knee osteoarthritis.

Eligibility Criteria

Inclusion Criteria

  • Age 60 or older
  • Symptomatic knee osteoarthritis (knee osteoarthritis diagnosed by x-ray and frequent knee symptoms)

Exclusion Criteria

  • bilateral knee replacement
  • acute or terminal illness
  • unstable cardiovascular condition or other medical conditions that may impair ability to participate such as pulmonary disease requiring use of supplement oxygen, or current medical condition that affects walking, or lower limb musculoskeletal surgery in the past 6 months
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00844558). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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