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Phase 3 N=4,200 Randomized Quadruple-blind Treatment

Telephone Counseling and the Distribution of Nicotine Patches to Smokers

Smoking Cessation

Enrolled (actual)
4,200
Serious AEs
0.0%
Results posted
Feb 2020
Primary outcome: Primary: Number of Participants With Six-month Continuous Abstinence From Cigarettes — 70; 101; 190 Participants

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Nicotine Patch (Drug); Telephone Counseling (Behavioral); Placebo (Drug); Self-Help Materials (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of California, San Diego
Primary completion
Oct 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Six-month Continuous Abstinence From Cigarettes
70; 101; 190
SECONDARY
Number of Participants Quit for 30-days at 2-months Post Enrollment
136; 173; 334

Summary

The primary purpose of this study is to determine the effects of distributing free nicotine replacement therapy (NRT) to tobacco quitline callers directly. Specifically, this study aims to: 1. Test if sending active nicotine patches directly will lead to a higher quit rate, compared to a condition where the quitline assists the smokers to obtain patches by other means (e.g. via their health plans). 2. Test if sending placebo patches directly will also lead to a higher quit rate. 3. Test if quitline counseling increases the quit rate when the smokers already receive the nicotine patches.

Eligibility Criteria

Inclusion Criteria

  • >= 18 years old
  • Daily smoker
  • >=6 cigarettes per day
  • Ready to quit within one month
  • First time quitline caller
  • Valid phone number
  • Valid address (no P.O. boxes)
  • California resident
  • Agree to participate in study and evaluation
  • English or Spanish speaking

Exclusion Criteria

  • Uses other form of tobacco
  • Use of Zyban or Chantix
  • One of the following conditions: Severe allergy to adhesive tape, Arrhythmia, Angina, Heart attack within last year, Stroke within last year, Uncontrolled high blood pressure, Insulin-dependent diabetes, Pregnancy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00851357). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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