Phase 3
Completed N=77
Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery?
Source: ClinicalTrials.gov NCT00853905 ↗Enrolled (actual)
77
Serious AEs
0.0%
Results posted
Mar 2016
Primary outcomePrimary: Intraocular Pressure (IOP) — 16.1; 12.8; 11.7; 11.8 mm Hg
◆ Published Evidence
Emerging
10citations · ~1 / year
Intracameral triamcinolone acetonide in glaucoma surgery: a prospective randomized controlled trial.
Summary
The investigators hypothesize that intracameral Triesence during glaucoma surgery will provide lower intraocular pressure through better control of ocular inflammation, thus leading to a more successful filtering procedure.
Linked Publications
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Intracameral triamcinolone acetonide in glaucoma surgery: a prospective randomized controlled trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Intraocular Pressure (IOP) |
16.1; 12.8; 11.7; 11.8; 16.1; 14.4 | — |
| SECONDARY Anterior Chamber Inflammation (Flare) |
0.4; 1.0; 0.6; 0.4; 0.3; 0.2 | — |
| SECONDARY Bleb Appearance |
1.7; 2.1; 1.7; 1.9; 2.2; 1.9 | — |
| SECONDARY Patient Comfort |
0.3; 0.1; 0.6; 0.3; 0.3; 0.6 | — |
| SECONDARY Ocular Hypotensive Medications |
0.03; 0.06; 0.1; 0.03; 0.08; 0.22 | — |
Eligibility Criteria
Inclusion Criteria
- glaucoma patients requiring surgery (Trabeculectomy or Express Shunt; Trabeculectomy plus Phacoemulsification and Interocular Lens Implant; Baerveldt Tube; Ahmed Tube; Molteno Tube)
- primary open angle glaucoma
- primary angle-closure glaucoma
- pseudoexfoliation glaucoma
- pigmentary glaucoma
- traumatic glaucoma
- neovascular glaucoma
Exclusion Criteria
- patients that are pregnant, nursing, or not using adequate contraception
- any other eye surgery except cataract surgery
- an infection, inflammation, or any abnormality preventing measurement of eye pressure
- enrolled in another investigational study
Data sourced from ClinicalTrials.gov (NCT00853905) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.