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Ophthalmology
RCT
Perioperative taVNS Reduces Pain and Insomnia After Glaucoma Surgery
Vagus nerve stimulation lowers pain after glaucoma surgery
This randomized trial of 94 patients undergoing glaucoma surgery found that perioperative transcutaneous auricular vagus nerve stimulation (…
A trial found that vagus nerve stimulation reduced pain and improved sleep for patients having glaucoma surgery under general anesthesia.
Apr 29, 2026
Ophthalmology
Retrospective review links higher TAPE score to better SLT outcomes in glaucoma
New laser settings help lower eye pressure for years without extra drops
This retrospective review of 62 eyes undergoing lower-energy SLT found that higher TAPE scores were associated with lower IOP at 2 months an…
A new way to tune laser energy for glaucoma could keep pressure low for years while avoiding the need for daily eye drops.
medRxiv
Apr 29, 2026
Ophthalmology
Review of portable visual field devices shows higher patient preference over table-mounted analyzers in rural glaucoma care.
Portable eye tests beat old machines for rural patients
This mixed methods review analyzed patient preferences among 271 respondents at three Alabama Federally Qualified Health Centers. Results in…
Rural patients with glaucoma preferred portable virtual reality eye tests over traditional machines, reporting higher satisfaction and comfo…
medRxiv
Apr 26, 2026
Genetics & Precision Medicine
Cohort
Polygenic risk score enrichment reduces sample size needs for coronary artery disease and inflammatory bowel disease trials.
Smarter trial designs could cut study sizes by 60% for heart disease
This in silico observational cohort study used UK Biobank data to model trial designs enriched for polygenic risk. Enriching to the upper 25…
Using genetic risk scores to pick high-risk volunteers could shrink trial sizes by 60% for heart disease and 78% for IBD, speeding up resear…
medRxiv
Apr 23, 2026
Ophthalmology
Preclinical study tests AI pipeline for glaucoma detection using Harvard dataset
New AI System Catches Glaucoma Cases That Other Tools Miss
This preclinical study evaluated a two-tier AI diagnostic pipeline for glaucoma using the Harvard Glaucoma Detection and Progression dataset…
This approach may help doctors spot glaucoma earlier by using AI to double-check its own uncertain findings.
medRxiv
Apr 23, 2026
Ophthalmology
Modeling study finds variable ciliary body anatomy may affect subliminal cyclophotocoagulation dosing in glaucoma
Your Glaucoma Laser Treatment Might Be Missing the Target
A modeling study of 24,001 eyes from a biometric database estimated ciliary body arc length (ECBAL) for subliminal transscleral cyclophotoco…
A new eye model reveals that using a one-size-fits-all approach for a common glaucoma laser could be leading to under- or over-treatment for…
medRxiv
Apr 11, 2026
Ophthalmology
RCT
Microdrop device reduces bottle exhaustion and adverse events in glaucoma patients on monotherapy
Small study finds microdrop device may lower eye pressure and reduce medication waste in glaucoma
A prospective randomized crossover trial in 29 adults with stable glaucoma or ocular hypertension on monotherapy found microdrops decreased …
A new device lowers eye pressure better than standard drops and cuts waste, stopping 83% of users from running out of medication early.
Apr 3, 2026
Ophthalmology
Meta-analysis
Meta-analysis finds nearly half of Ethiopian glaucoma patients report poor quality of life
Nearly half of glaucoma patients in Ethiopian hospital studies report poor quality of life
A systematic review and meta-analysis of four hospital-based studies in Ethiopia found a pooled prevalence of poor quality of life of 47% am…
Nearly half of Ethiopian glaucoma patients report poor quality of life due to vision loss, limited care access, and economic hardship.
Apr 2, 2026
Ophthalmology
Meta-analysis
CW-CPC shows greater sustained IOP reduction than MP-CPC in pediatric glaucoma meta-analysis
Review finds continuous wave laser more effective than micropulse for childhood glaucoma pressure
A systematic review and meta-analysis comparing cyclophotocoagulation techniques in children with glaucoma found continuous wave (CW-CPC) pr…
A review of past research shows the older continuous wave laser lowers eye pressure better than the newer micropulse method in children with…
Apr 2, 2026