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N/A Completed N=177

Obesity and the Initiation of Knee Osteoarthritis

Source: ClinicalTrials.gov NCT00856739 ↗
Enrolled (actual)
177
Serious AEs
Results posted
Dec 2014
Primary outcomePrimary: Gait Knee Adduction Moment — 3.14; 2.39 percent body weight (N)*height (m)

Summary

Healthy adults aged 20-60 of varying weights will participate in this minimally invasive study. There is one 4-hour appointment for which subjects are paid $120. The tests involve: 1 tube blood draw, 1 gait test (motion capture) and 1 MR of both knees.

Outcome Measures

OutcomeResultp-value
PRIMARY
Gait Knee Adduction Moment
3.14; 2.39
PRIMARY
Cartilage Thickness
1.069; 1.04571; 1.051; 1.069

Eligibility Criteria

Inclusion Criteria

  • Healthy Adults aged 20-60 who have no history of LE surgery
  • Healthy adults able to walk 30 minutes
  • Healthy adults able to have MR

Exclusion Criteria

  • Adults who have had LE surgery
  • Adults cannot walk 30 minutes
  • Adults who cannot tolerate MR
  • Adults with osteoarthritis
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00856739). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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