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N/A N=141 Randomized Quadruple-blind Treatment

Trial of Montelukast for Treatment of Acute Bronchiolitis

Bronchiolitis

Enrolled (actual)
141
Serious AEs
0.0%
Results posted
Jun 2015
Primary outcome: Primary: Duration of Cough — 13; 11 days

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
montelukast sodium (Drug); sucrose (Other)
Age
Pediatric · 0+ yrs
Sex
All
Sponsor
Medical College of Wisconsin
Primary completion
Jul 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Duration of Cough
13; 11

Summary

The primary rationale for this study is to evaluate the effect of once daily montelukast on duration of acute illness in infants with first-time bronchiolitis.

Eligibility Criteria

Inclusion Criteria

  • Male or female infants aged 3 to 12 months of age
  • Diagnosis by emergency physician of bronchiolitis

Exclusion Criteria

  • Any previous episode, as determined by a physician, of wheezing, bronchiolitis or asthma
  • Any history of previous bronchodilator use prior to this illness
  • Treatment with corticosteroids in the 14 days prior to the current illness
  • Immunosuppression
  • Immunodeficiency
  • Caregiver does not speak English
  • Diagnosis by the treating ED physician of croup
  • Diagnosis by the treating ED physician of pneumonia
  • Caregiver does not have access to a telephone
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00863317). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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