Phase 2
Completed N=22
The Effect of Remote Ischemic Preconditioning Applied in Children the Day Before Open Heart Surgery
Source: ClinicalTrials.gov NCT00868101 ↗Enrolled (actual)
22
Serious AEs
0.0%
Results posted
Jan 2012
Primary outcomePrimary: IkB-alpha Expression — 4.1; 3.6 units on a scale
Summary
The study research is to analyse brief episodes of limb ischemia applied to children the day before open heart surgery as protection from myocardial injury induced by extracorporeal circulation.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY IkB-alpha Expression |
4.1; 3.6 | — |
| PRIMARY Interleucine 8 |
20.8; 32.2 | — |
| SECONDARY NT-proBNP |
8.565; 12.681 | — |
| SECONDARY Troponin I |
33.7; 22.3 | — |
Eligibility Criteria
Inclusion Criteria
- 1 month to 2 years age
- waiting for open heart surgery in hospital
- 2008, january to march
- Rachs-1, except the 1 category
Exclusion Criteria
- genetic syndromes
- infected children
- immunodeficiency
- immunosuppressor use
- no parents permission
Data sourced from ClinicalTrials.gov (NCT00868101). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.