N/A
N=40
Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study
Chronic Rhinosinusitis
Bottom Line
View on ClinicalTrials.gov: NCT00871286 ↗Enrolled (actual)
40
Serious AEs
—
Results posted
Jan 2012
Primary outcome: Primary: Number of Participants in Compliance With Medical Recommendations — 20; 10 participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Pre-treatment Sinus CT Scan (Procedure); Post-treatment Sinus CT Scan (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Northwestern University
- Primary completion
- Aug 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants in Compliance With Medical Recommendations |
20; 10 | — |
| PRIMARY Number of Participants Having a CT Done |
20; 9 | — |
Summary
The purpose of this research study is to determine whether or not computed tomography (CT) scans performed on patients with symptoms of chronic rhinosinusitis (CRS) but without any physical signs of the disease will (1) prove to be less expensive in the treatment and evaluation as compared to current practices, (2) avoid the use of unnecessary antibiotic prescriptions, and (3) provide a more efficient way to diagnose conditions in patients who have had CRS ruled out as a cause.
The investigators hypothesize that current guidelines, when applied to subjects with symptoms of CRS in the absence of physical signs may be associated with (1) increased unnecessary prescription of antibiotics, (2) delay in further essential workup, and (3) increased overall health care costs.
Eligibility Criteria
Inclusion Criteria
- Subjects actively meeting the symptomatic criteria for CRS as defined by the Taskforce on Rhinosinusitis but with physical and endoscopic examination that is within normal limits
Exclusion Criteria
- Subjects who are pregnant
- Subjects with a diagnosis of immune suppression or suspicion of malignancy that may be affecting the nose/paranasal sinuses
- Subjects who have had prior sinus surgery or who have been previously treated with a >3 week course of broad spectrum antibiotics for CRS
Data sourced from ClinicalTrials.gov (NCT00871286). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.