Multispecies animal models often fail to reflect human nasal sinus anatomy and physiology in chronic rhinosinusitis research
Scientists compare different animal models for studying human nose diseases to find better ways to test new treatments
This narrative review examines the efficiency of murine, sheep, and porcine models in representing human phenotypes for chronic rhinosinusit…
Researchers looked at mice, sheep, and pigs to see which ones best match human nose conditions. They found that simple models often fail to …
Meta-analysis of adjunctive therapies for recurrent rhinosinusitis shows improved outcomes with conventional treatment
Beyond Surgery: Simple Add-Ons Cut Sinus Problems in Half
This meta-analysis evaluated adjunctive therapies, including nasal irrigation and steroid-eluting implants, combined with standard treatment…
Adding simple therapies like nasal rinses or steroid implants to standard sinus treatment can dramatically cut symptoms and prevent future i…
Biofilm-driven chronic rhinosinusitis: review reframes recalcitrance as immune and ecological dysregulation
A narrative review discusses chronic rhinosinusitis without reporting new study data or results
This narrative review reframes treatment-recalcitrant chronic rhinosinusitis (CRS) as a biofilm-driven disorder in which microbial communiti…
This document is a narrative review about chronic rhinosinusitis, a condition involving long-term inflammation of the nasal sinuses.
Meta-analysis identifies genetic loci and proteins associated with chronic rhinosinusitis and nasal polyps
Why do some people get severe sinus inflammation while others stay healthy?
This meta-analysis of six biobanks utilized comparative genomic analyses and proteome-wide Mendelian methods to investigate chronic rhinosin…
A massive DNA analysis maps the genetic roots of severe sinus inflammation, revealing specific immune system factors that make some people f…