Phase 2
Completed N=314
Strategies To Prevent Pneumonia 2 (SToPP2)
Infections, Hospital · ventilator-associated pneumonia · Mechanical Ventilation Complication
Source: ClinicalTrials.gov NCT00893763 ↗
Enrolled (actual)
314
Serious AEs
0.0%
Results posted
Jan 2016
Primary outcomePrimary: Development of VAP (Clinical Pulmonary Infection Score) — 4.13; 4.45 units on a scale — p=0.1763
Summary
Ventilator-associated pneumonia (VAP) is a serious complication in mechanically ventilated critically ill patients. The intervention tested in this project (swabbing the mouth with chlorhexidine before the endotracheal tube is inserted) could reduce the risk of ventilator-associated pneumonia.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Development of VAP (Clinical Pulmonary Infection Score) |
4.13; 4.45 | 0.1763 |
| SECONDARY Endotracheal Tube Colonization |
18.6; 17.5 | — |
| SECONDARY Serum Cytokines |
— | — |
| SECONDARY Serum Procalcitonin |
— | — |
Eligibility Criteria
Inclusion Criteria
- Need for intubation
Exclusion Criteria
- Pneumonia at the time of intubation
Data sourced from ClinicalTrials.gov (NCT00893763). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.