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N/A N=24 Randomized Treatment

Omentectomy and Metabolic Syndrome

Metabolic Syndrome · Morbid Obesity

Enrolled (actual)
24
Serious AEs
4.2%
Results posted
Jun 2009
Primary outcome: Primary: Components of Metabolic Syndrome (Body Mass Index) — 44.9; 44.5 Kg/m2 — p=0.79

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Laparoscopic Roux-en-Y Gastric Bypass (Procedure); Omentectomy (Procedure)
Age
Adult, Older Adult · 20+ yrs
Sex
All
Sponsor
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Primary completion
Oct 2007

Outcome Measures

OutcomeResultp-value
PRIMARY
Components of Metabolic Syndrome (Body Mass Index)
30.3; 30.7 0.76
PRIMARY
Components of Metabolic Syndrome (Body Mass Index)
30.3; 30.7 0.76
PRIMARY
Components of Metabolic Syndrome (Body Mass Index)
30.3; 30.7 0.76
PRIMARY
Components of Metabolic Syndrome (Body Mass Index)
30.3; 30.7 0.76
PRIMARY
Components of Metabolic Syndrome (Body Mass Index)
30.3; 30.7 0.76
PRIMARY
Components of Metabolic Syndrome (Systolic Blood Pressure)
116.7; 124.3 0.15
PRIMARY
Components of Metabolic Syndrome (Systolic Blood Pressure)
116.7; 124.3 0.15
PRIMARY
Components of Metabolic Syndrome (Systolic Blood Pressure)
116.7; 124.3 0.15
PRIMARY
Components of Metabolic Syndrome (Systolic Blood Pressure)
116.7; 124.3 0.15
PRIMARY
Components of Metabolic Syndrome (Systolic Blood Pressure)
116.7; 124.3 0.15
PRIMARY
Components of Metabolic Syndrome (Diastolic Blood Pressure)
71.7; 76.6 0.21
PRIMARY
Components of Metabolic Syndrome (Diastolic Blood Pressure)
71.7; 76.6 0.21
PRIMARY
Components of Metabolic Syndrome (Diastolic Blood Pressure)
71.7; 76.6 0.21
PRIMARY
Components of Metabolic Syndrome (Diastolic Blood Pressure)
71.7; 76.6 0.21
PRIMARY
Components of Metabolic Syndrome (Diastolic Blood Pressure)
71.7; 76.6 0.21
PRIMARY
Components of Metabolic Syndrome (Glucose)
88.1; 89.3 0.75
PRIMARY
Components of Metabolic Syndrome (Glucose)
88.1; 89.3 0.75
PRIMARY
Components of Metabolic Syndrome (Glucose)
88.1; 89.3 0.75
PRIMARY
Components of Metabolic Syndrome (Glucose)
88.1; 89.3 0.75
PRIMARY
Components of Metabolic Syndrome (Glucose)
88.1; 89.3 0.75
PRIMARY
Components of Metabolic Syndrome (Insulin)
7.3; 6.6 0.67
PRIMARY
Components of Metabolic Syndrome (Insulin)
7.3; 6.6 0.67
PRIMARY
Components of Metabolic Syndrome (Insulin)
7.3; 6.6 0.67
PRIMARY
Components of Metabolic Syndrome (Insulin)
7.3; 6.6 0.67
PRIMARY
Components of Metabolic Syndrome (Total Cholesterol)
157.4; 166.6 0.42
PRIMARY
Components of Metabolic Syndrome (Total Cholesterol)
157.4; 166.6 0.42
PRIMARY
Components of Metabolic Syndrome (Total Cholesterol)
157.4; 166.6 0.42
PRIMARY
Components of Metabolic Syndrome (Total Cholesterol)
157.4; 166.6 0.42
PRIMARY
Components of Metabolic Syndrome (Total Cholesterol)
157.4; 166.6 0.42
PRIMARY
Components of Metabolic Syndrome (Triglycerides)
99.1; 118 0.40
PRIMARY
Components of Metabolic Syndrome (Triglycerides)
99.1; 118 0.40
PRIMARY
Components of Metabolic Syndrome (Triglycerides)
99.1; 118 0.40
PRIMARY
Components of Metabolic Syndrome (Triglycerides)
99.1; 118 0.40
PRIMARY
Components of Metabolic Syndrome (Triglycerides)
99.1; 118 0.40
PRIMARY
Components of Metabolic Syndrome (Low-Density Lipoproteins)
95; 94.6 0.96
PRIMARY
Components of Metabolic Syndrome (Low-Density Lipoproteins)
95; 94.6 0.96
PRIMARY
Components of Metabolic Syndrome (Low-Density Lipoproteins)
95; 94.6 0.96
PRIMARY
Components of Metabolic Syndrome (Low-Density Lipoproteins)
95; 94.6 0.96
PRIMARY
Components of Metabolic Syndrome (Low-Density Lipoproteins)
95; 94.6 0.96
PRIMARY
Components of Metabolic Syndrome (High-Density Lipoproteins)
42.9; 45.8 0.55
PRIMARY
Components of Metabolic Syndrome (High-Density Lipoproteins)
42.9; 45.8 0.55
PRIMARY
Components of Metabolic Syndrome (High-Density Lipoproteins)
42.9; 45.8 0.55
PRIMARY
Components of Metabolic Syndrome (High-Density Lipoproteins)
42.9; 45.8 0.55
PRIMARY
Components of Metabolic Syndrome (High-Density Lipoproteins)
42.9; 45.8 0.55
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
4.3; 6.0 0.57
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
4.3; 6.0 0.57
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
4.3; 6.0 0.57
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
4.3; 6.0 0.57
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
8.9; 2.8 0.42
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
8.9; 2.8 0.42
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
8.9; 2.8 0.42
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
8.9; 2.8 0.42
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
5.9; 4.8 0.71
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
5.9; 4.8 0.71
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
5.9; 4.8 0.71
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
5.9; 4.8 0.71
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Leptin)
55; 87 0.59
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Leptin)
55; 87 0.59
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Leptin)
55; 87 0.59
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Leptin)
55; 87 0.59
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
18.9; 16.4 0.56
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
18.9; 16.4 0.56
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
18.9; 16.4 0.56
SECONDARY
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
18.9; 16.4 0.56

Summary

The aim of the present study was to evaluate the additional effect of sudden visceral fat reduction by omentectomy on Metabolic Syndrome, acute phase reactants and inflammatory mediators in patients with morbid obesity undergoing Laparoscopic Roux-en-Y Gastric Bypass.

Eligibility Criteria

Inclusion Criteria

  • BMI > 35 Kg/m2
  • Metabolic syndrome diagnosed

Exclusion Criteria

  • Type 1 diabetes
  • Uncontrolled type 2 diabetes
  • Cirrhosis or active hepatitis
  • Pregnancy
  • Recent MI or stroke
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00923260). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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