N/A
Completed N=265
PC-Based Cognitive Rehabilitation for Traumatic Brain Injury (TBI)
Source: ClinicalTrials.gov NCT00927576 ↗Enrolled (actual)
265
Serious AEs
0.0%
Results posted
Jul 2015
Primary outcomePrimary: Performance in TBI Patients and Controls — 237.8; 231.5; 228.0; 280.0 ms — p=< 0.001
Summary
The investigators evaluated whether it was possible to improve the measurement of memory, attention, and executive function in patients who have suffered traumatic brain injury through the use of computer-based testing.
Note: the original design of the study was altered due to failure to recruit sufficient numbers of patients who were willing to undergo prolonged cognitive training.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Performance in TBI Patients and Controls |
237.8; 231.5; 228.0; 280.0 | < 0.001 sig |
Eligibility Criteria
Inclusion Criteria
Control subjects were required to meet the following inclusion criteria:
- (a) fluency in the English language
- (b) no current or prior history of bipolar disorder, mania, or schizophrenia
- (c) no current substance abuse
- (d) no concurrent history of neurologic disease known to affect cognitive functioning
- (e) on a stable dosage of any required medication
- (f) auditory functioning sufficient to understanding normal conversational speech and visual acuity normal or corrected to 20/40 or better
Exclusion criteria
- History of TBI
Exclusion Criteria for TBI patients:
- TBI patients had to meet the same inclusion criteria as the controls with the exception that they were required to have a history of TBI. They also had to be in the chronic phase, i.e., 1-4 yrs post-injury.
- Exclusion criteria:
- current substance abuse
- current psychiatric diagnosis other than PTSD
Data sourced from ClinicalTrials.gov (NCT00927576). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.