N/A
Completed N=20
Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack
Source: ClinicalTrials.gov NCT00929994 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Apr 2019
Primary outcomePrimary: Functional Walk Test — 498.4; 503.2; 564.2 meters — p==0.06
Summary
It is hypothesized that the addition of formal cardiac rehabilitation to standard care will result in long-term improvements in cardiovascular fitness and functional capacity in individuals who have suffered a transient ischemic attack (TIA) or minor stroke.
Furthermore, it is proposed that the addition of cardiac rehabilitation will influence depressive symptoms and cognition.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Functional Walk Test |
498.4; 503.2; 564.2 | =0.06 |
| PRIMARY Cardiovascular Fitness (VO2peak) |
16.7; 19.1 | 0.01 sig |
| SECONDARY Center for Epidemiologic Studies Depression Scale (CES-D). |
6.5; 7.6; 4.3 | 0.04 sig |
| SECONDARY Cognition |
26.5; 26.8; 27.1 | >0.05 |
Eligibility Criteria
Inclusion Criteria
- Diagnosed with TIA
- Three months post-TIA
- Ability to understand the process and instructions for exercise training and provide informed consent
Exclusion Criteria
- Resting Blood Pressure greater than 160/100 despite medication
- Other cardiovascular morbidity which would limit exercise tolerance (heart failure, abnormal BP responses or STsegment depression > 2 mm, symptomatic aortic stenosis, complex arrhythmias)
- Current and extensive exercise participation
- Hypertrophic Cardiomyopathy
- Unstable Angina
- Orthostatic BP decrease of > 20 mm Hg with symptoms
- Other musculoskeletal impairments which would limit the participants ability to walk sufficient durations
- Pain or other co-morbidities (e.g., unclipped aneurysms, uncontrolled seizures etc.) which would preclude participation
- Cognitive or behavioural issues that would limit participation in exercise testing and training
Data sourced from ClinicalTrials.gov (NCT00929994). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.