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Transient Ischemic Attack

Part of Cerebral ischemia

11 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Transient Ischemic Attack

22 trials tracked for Transient Ischemic Attack: 4 in phase 3 or 4 and 3 with published results. The most-cited published study has 108 citations.

22Trials tracked
4Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 3 4 Phase 2 2 Other / NA 16
  1. Phase 3 [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] Completed · 108 cited
  2. Phase 3 THALES - Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death Completed · 102 cited
  3. Phase 3 Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation Completed · 31 cited
  4. Phase 3 Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease Completed
  5. Phase 2 Revacept in Symptomatic Carotid Stenosis Completed
  6. Phase 2 Rivaroxaban Versus Warfarin in Acute Ischemic Stroke With Atrial Fibrillation Completed
Show 16 more trials
  1. N/A Comprehensive Post-Acute Stroke Services Completed
  2. N/A Improving Coordination and Transitions of Care in Stroke Patients Completed
  3. N/A Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coordination Completed
  4. N/A Connected Health Blood Pressure Monitoring In Stroke and TIA Patients Completed
  5. N/A Prevent Return of Stroke Study Completed
  6. N/A Neuropsychometric Outcome After Carotid Endarterectomy Completed
  7. N/A Protocol-guided Rapid Evaluation of Veterans Experiencing New Transient Neurological Symptoms Completed
  8. N/A Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS) Completed
  9. N/A Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack Completed
  10. N/A Stroke Education Intervention Trial - Pilot Completed
  11. N/A VITATOPS: A Study of VITAmins TO Prevent Stroke Completed
  12. N/A RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt Completed
  13. N/A Canadian Pradaxa Acute Stroke Safety Study Completed
  14. N/A GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients Completed
  15. N/A Sleep Apnea in TIA/Stroke: Reducing Cardiovascular Risk With Positive Airway Pressure Completed
  16. N/A Adapting Tools to Implement Stroke Risk Management to Veterans Completed

Showing the 22 most-cited and recently-updated of 22 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Transient Ischemic Attack: what the trials found

Ticagrelor was shown to significantly reduce the composite outcome of subsequent stroke or death (p=0.015) and specifically reduced the incidence of ischemic stroke (p=0.004). However, it did not result in a statistically significant difference in patients with a Modified Rankin Scale score greater than 1 at visit 3 (p=0.613).

In another trial evaluating ticagrelor, there was a statistically significant reduction in the number of subjects with new brain infarcts or recurrent strokes (p=0.024) and an improvement in freedom from recurrent ischemic stroke (p=0.001) compared to alternative medical therapies.

Apixaban and CPAP therapy for newly diagnosed obstructive sleep apnea (OSA) were evaluated in separate established trials.

Recent results — preliminary, needs further review

  • Care coordination delivered based on perceived need is currently being evaluated in a recent study.

For the clinician treating this condition

  • Ticagrelor is associated with significant reductions in ischemic stroke and the composite of subsequent stroke or death.
  • While ticagrelor impacts stroke frequency, it did not show a statistically significant impact on Modified Rankin Scale scores at specific follow-up intervals.

AI synthesis of 0 cited trials, updated Jun 23, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Questions about Transient Ischemic Attack

Can I expect sex differences in my cardiovascular death risk after a TIA?

Yes, sex may influence cardiovascular death risk after TIA, but evidence is mixed; some studies show no significant difference, while others suggest women may have lower risk.

Full answer →
Do men and women have different outcomes after a TIA with atrial fibrillation?

Research suggests men and women with TIA and atrial fibrillation may have similar risks of stroke recurrence, but men may face higher risk of cognitive impairment and major vascular events.

Full answer →
Does having glomerular hyperfiltration mean I have higher mortality after a TIA?

Yes, having glomerular hyperfiltration is linked to a higher risk of death after a stroke or transient ischemic attack (TIA).

Full answer →