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N/A N=270 Randomized Single-blind Treatment

Trial Comparing Three Different Devices for Kidney Stone Removal During Percutaneous Surgery

Kidney Stones

Enrolled (actual)
270
Serious AEs
0.0%
Results posted
Jul 2019
Primary outcome: Primary: Stone Clearance Time in mm2/Min — 24.0; 28.9; 32.3 mm^2/min

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Cyberwand (Device); Stonebreaker (Device); Lithoclast Select (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Indiana Kidney Stone Institute
Primary completion
Oct 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Stone Clearance Time in mm2/Min
24.0; 28.9; 32.3
SECONDARY
Stone-free After First Procedure
33; 43; 39
SECONDARY
Secondary Procedure Required
15; 16; 24
SECONDARY
Ureteral Stent Placed
3; 4; 5
SECONDARY
Nephrostomy Tube Placed
55; 59; 63
SECONDARY
Use of Other Device
8; 9; 5
SECONDARY
EBL>400mL
4; 2; 3
SECONDARY
RBC Transfusion
3; 2; 2
SECONDARY
Length of Stay
1.9; 2.5; 2.6
SECONDARY
Post-operative Complications
10; 10; 11

Summary

The investigators plan to compare three different devices that are used to break up large kidney stones during surgery for removal to see if one is faster or more efficient than the others.

Eligibility Criteria

Inclusion Criteria

  • Scheduled to undergo percutaneous nephrolithotomy for at least one kidney stone measuring 2 cm or greater
  • Stone easily visible/measurable on plain abdominal imaging (KUB) or CT scan preoperatively
  • Age 18 years or older
  • Able to give informed consent

Exclusion Criteria

  • Size of single largest stone less than 2 cm
  • Pregnancy
  • Active urinary tract infection
  • Extracorporeal shockwave lithotripsy within the last three months
  • Complex stone anticipating multiple access sites
  • Stones that are not clearly able to be measured on KUB or CT scan
  • Inability to give informed consent
  • Age less than 18 years
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00952315). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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