Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
Questions about Chronic Kidney Disease
Does taking NSAIDs during pregnancy increase the risk of kidney disease in my child?
A large review of seven studies found that taking NSAIDs during pregnancy is linked to a higher risk of kidney disease in children, with the risk increasing when used in the second and third trimesters.
Full answer →Are there new guidelines for kidney cancer based on recent 2025 trials?
Yes, the 2025 EAU guidelines update kidney cancer care with new recommendations on stereotactic body radiotherapy, adjuvant therapy, and systemic treatments for clear-cell and hereditary RCC.
Full answer →How can artificial intelligence help patients with kidney cancer in surgery?
Artificial intelligence helps kidney cancer patients by improving tumor detection on scans, planning robotic surgeries, and predicting surgical outcomes to reduce complications.
Full answer →Are complication risks for kidney stone surgery higher in elderly patients?
Yes, elderly patients have higher risks of sepsis after PCNL, but overall complication rates are similar to younger patients for most kidney stone surgeries.
Full answer →Do complement pathways play a role in kidney diseases affecting my transplant?
Yes, complement pathways are involved in kidney transplant rejection, including antibody-mediated rejection, and may be targeted for therapy.
Full answer →What mechanisms link obesity to inflammation in chronic kidney disease?
Obesity fuels kidney inflammation through adipose tissue dysfunction, lipotoxicity, altered secretion of inflammatory factors, and gut-derived uremic toxins, creating a vicious cycle that worsens chronic kidney disease.
Full answer →Can layered data models help doctors find my risk for diabetic kidney disease earlier?
Yes, layered data models that combine clinical, lab, medication, and social data can help doctors detect diabetic kidney disease risk earlier than traditional methods alone.
Full answer →Can a machine learning model find hidden diabetic kidney disease while I am hospitalized?
Yes, a machine learning model using routine hospital data can detect hidden diabetic kidney disease, even when standard tests appear normal.
Full answer →All Chronic Kidney Disease Articles
- Roxadustat increases odds of vascular access thrombosis and all-cause mortality in patients with chronic kidney disease
- Ambulatory hypertension in pediatric chronic kidney disease patients increases risk of left ventricular hypertrophy
- Cystatin C shows good diagnostic performance with an AUC of 0.88 for early detection of SA-AKI
- Risk-adapted HLA delisting and imlifidase enable deceased-donor kidney transplantation for highly sensitized candidates
- Semaglutide reduces risk of kidney decline or death in type 2 diabetes and CKD
- Gut microbiota dysbiosis and microbial metabolites impair renal function in sepsis-associated acute kidney injury
- Jinlida Granule reduces serum creatinine and HbA1c in diabetic kidney disease patients across a meta-analysis
- Steroid avoidance may reduce death and diabetes after kidney transplant but raises rejection risk
- ILC dysregulation and gut microbiota dysbiosis may drive kidney disease via the microbiota-gut-kidney axis
- Kidney transplantation reduces left-ventricular mass index by 22 g/m² in end-stage kidney disease
- Fluoroless ultrasound-guided techniques lower complications in percutaneous nephrolithotomy with equivalent stone-free rates
- ECIRS triples stone-free odds versus PCNL in large kidney stones, meta-analysis finds
- Chronic kidney disease linked to shorter leukocyte telomere length in meta-analysis
- Education and behavior interventions reduce burden for CKD caregivers in a systematic review
- Gut dysbiosis contributes to CKD complications via interconnected pathways, though mechanistic validation remains incomplete
- Exosomes show promise as biomarkers and therapeutic vectors in diabetic complications
- Cerivastatin best for total cholesterol, simvastatin for LDL-C in DKD with hyperlipidemia
- Nutritional vitamin D reduces CRP and improves albumin in maintenance hemodialysis patients
- Pyrethroid insecticide exposure linked to acute kidney injury in a 55-year-old male
- Case report confirms X-linked Alport syndrome diagnosis in a young girl with family history
- Clinical and laboratory abnormalities linked to higher mortality in malaria patients with acute kidney injury
- Complement activation in acute kidney injury a convergent mechanism
- Systematic review and meta-analysis links prenatal NSAIDs to higher kidney disease risk in children
- Systematic review and meta-analysis of prediction models for diabetic kidney disease progression to ESRD
- Systematic review and meta-analysis on FGF23 levels in diabetic kidney disease
- Mini review of Explainable AI for kidney stone segmentation in resource-constrained settings
- Narrative review of salvianolic acids for kidney disease pharmacokinetics and anti-fibrotic activity
- Narrative review examines ureteroscopy with negative-pressure suction sheath for kidney and ureteral stones
- Meta-analysis finds lower bleeding risk with apixaban and rivaroxaban vs VKAs in dialysis patients with AF
- Narrative review explores gut-kidney axis in chronic kidney disease progression
- Meta-analysis finds SGLT2 inhibitors reduce cardiac arrest risk in CKD patients
- Combining finerenone with SGLT2 inhibitors lowers mortality and cardiovascular events in diabetic chronic kidney disease patients
- Meta-analysis links acute kidney injury to increased stroke, delirium, and dementia risk
- Narrative review of lung, breast, liver, and kidney cancer evidence
- Case report suggests hemorrhagic fever with renal syndrome may trigger secondary hyperparathyroidism
- Digital decision support tools showed parallel improvements with no between-group differences in kidney outcomes among adults with chronic kidney disease in Chinese primary care centers
- HIF-PHIs alter lipid profiles in CKD patients but show no cardiovascular mortality difference
- Pentoxifylline Improves Kidney Function and Reduces Inflammation in CKD
- Complication risks in elderly patients undergoing percutaneous nephrolithotomy compared to younger populations
- CABG versus PCI in high-risk coronary revascularisation patients shows mixed outcomes over 5 years
- Arterioarterial grafts show high patency in hemodialysis patients
- Systematic review links gestational diabetes to higher maternal CKD risk in large cohort analysis
- Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients
- Meta-analysis shows associations between hypothyroidism and increased chronic kidney disease prevalence
- RIRS with TFLLT shows similar stone-free rates to PNL for 20-30 mm kidney stones in adults
- Hypophosphatemia during KRT linked to fewer ventilator-free days in critically ill patients
- Kidney-directed SBRT shows modest renal function decline in inoperable patients
- Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients
- Systematic review and meta-analysis of health coaching interventions in chronic kidney disease patients
- Meta-analysis finds GLP-1RA plus SGLT2i reduces UACR in type 2 diabetes with kidney disease
- Systematic review and meta-analysis of MRAs in dialysis patients shows reduced nonfatal CVD events but elevated hyperkalemia and gynecomastia risks
- Permanent night shift work associated with increased chronic kidney disease risk in UK Biobank participants
- Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
- Systematic Review Links Lysosomal Pathways to Autoimmune Kidney Disease Progression
- Machine learning model identifies RLS in ESRD patients with AUC 0.791
- Mini Review Covers Complement Pathways in Kidney Diseases and Injuries
- Narrative review discusses renal risks in inflammatory bowel disease patients
- Higher sdLDL-C Linked to Lower Kidney Stone Risk in Two Cohorts
- Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
- White blood cell indicators predict acute kidney injury in critically ill advanced colorectal cancer patients
- Higher TyG index linked to increased renal function progression risk in patients with CKD stages 3–4
- Observational study links cutaneous microvascular function to chronic kidney disease severity
- Individual-participant data meta-analysis shows blood-pressure lowering reduces cardiovascular risk in CKD and non-CKD populations
- Machine learning model improves early detection of occult diabetic kidney disease in hospitalized patients
- Oral beraprost extends median survival in dogs with IRIS stage 2 chronic kidney disease compared to historical controls
- Circulating SVEP1 Protein Associated With Major Adverse Cardiovascular Events in Hemodialysis Patients
- Cross-sectional study links declining nephron number to CKD stage in diabetic nephropathy
- Meta-analysis of dapagliflozin for renal outcomes in type 2 diabetes and CKD
- High-altitude ICU study finds 21% AKI incidence in neurocritical patients
- Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
- Narrative review supports SGLT-2i use in cardiovascular-kidney-metabolic syndrome
- Systematic review and meta-analysis shows dapagliflozin increases hemoglobin in chronic kidney disease patients
- Systematic review and meta-analysis shows exercise improves depression and quality of life in hemodialysis patients
- Observational review of layered data models improves DKD risk detection in type 2 diabetes cohorts
- Systematic review of anti-IL-5 biologics in hypereosinophilic syndrome kidney disease reports low certainty evidence
- Inflammatory indices associated with increased chronic kidney disease risk in coronary artery disease cohort
- Systematic review examines oral microbiota associations with chronic kidney disease and early childhood caries
- Flexible suction sheath outperforms conventional sheath in renal stone surgery
- Conservative fluid management shows no difference in tissue perfusion or kidney injury in critically ill adults
- Preclinical analysis of gnomAD and ClinVar databases on ADPLD variant frequencies
- Dyslipidemia linked to poorer renal survival in primary IgA nephropathy patients
- Pilot RCT tests digital inclusion intervention for adults with chronic kidney disease
- CRRT after heart transplantation linked to preoperative hemoglobin and VIS score in cohort study
- Chemotherapy-related renal injury incidence and risk factors in patients with malignant tumors
- Updated PIRCHE-T2 model improves dnDSA risk stratification in kidney transplant recipients
- 24-hour diastolic BP variability linked to renal decline in diabetic kidney disease
- O. vulgatum consumption linked to rhabdomyolysis and acute kidney injury in 10 patients
- Single-centre observational study on hemodialysis duration and outcomes in end-stage renal disease
- Systematic Review Examines Therapeutic Strategies Targeting Renal ELD in Kidney Diseases
- Meta-analysis of nutrition education in adult dialysis patients shows improved knowledge and quality of life
- Review summarizes therapeutic strategies targeting cGAS-STING-macrophage axis for renal fibrosis and chronic kidney disease
- FluxPro-DKD fusion model integration shows higher AUC for early-stage DKD detection in type 2 diabetes
- Elevated TyG index linked to renal deterioration in CKD and hypertensive cohorts
- Meta-analysis links chronic kidney disease to higher mortality after intracerebral hemorrhage
- Meta-analysis of 24 animal studies shows emodin reduces kidney injury markers in preclinical models
- Gastrointestinal complications in cardiac surgery patients are linked to high mortality and multiorgan failure
- Minimum immunobiology packages may improve kidney transplant safety and equity in low- and middle-income settings
- Cross-Sectional Analysis of Protective Foot Sensation and Complications in 387 Type 2 Diabetes Patients
- Atherogenic index of plasma shows non-linear association with mortality in diabetic AKI patients
- Cryopreserved venous allografts increased cold ischemia time in living-donor kidney transplant recipients
- Body roundness index shows significant association with metabolic syndrome but constrained predictive ability for other CKM outcomes
- Total IgG Concentration Linked to Anemia in Hemodialysis Patients
- Multimodal AI applications in urologic oncology for prostate, bladder, and kidney cancers
- Narrative review suggests coordinated care models may strengthen European primary health care systems
- Physical exercise reduces all-cause mortality and improves outcomes in chronic kidney disease patients
- Retrospective analysis of PEW diagnosis prevalence and correlates in children with CKD stages 3-5D
- Carotid plaque measures predict coronary heart disease in CKD patients
- Proenkephalin A levels show no correlation with kidney or cardiac markers in hemodialysis patients
- NIID patients with kidney injury show higher immune markers compared to those without kidney injury
- Meta-analysis identifies risk factors for diabetic kidney disease in Asian patients with type 2 diabetes
- Cross-sectional study links CKD, sarcopenia, and undernutrition to CVD history in older Japanese adults
- Telemonitoring in adult kidney transplant recipients improved patient satisfaction and access to care
- Higher cumulative inflammatory-metabolic index linked to increased risk of rapid kidney function decline in older adults
- Network meta-analysis of novel antidiabetic drugs in T2DM with CKD shows sotagliflozin, empagliflozin, and semaglutide rank highest for cardiovascular and renal outcomes
- Oral semaglutide reduces composite heart failure outcomes in patients with type 2 diabetes and heart failure history
- Antimicrobial stewardship bundle improved perioperative antibiotic protocol adherence in oncourology surgeries
- Genetic correlation between kidney function and Alzheimer disease is absent in European and African ancestry cohorts
- CI-AKI in ACS patients undergoing PCI was associated with a 4.7-fold increased hazard of death within 90 days
- Systematic review of 2025 RCTs identifies new standards of care across genitourinary cancers
- ESKD Patients Had Higher ED Hospitalization, Mortality During COVID-19 Pandemic in South Korea
- Urinary podocin and nephrin show poor short-term prediction of DKD progression in type 2 diabetes
- Finerenone linked to improved KDIGO risk categories in T2D and CKD patients
- Network meta-analysis of sodium bicarbonate, cholecalciferol, and protein supplementation in 2,879 chronic kidney disease patients
- Higher C-reactive protein-to-lymphocyte ratio linked to proteinuric CKD in hypertensive patients
- Retrospective study identifies predictors for dialysis access steal syndrome in ESRD patients
- Hispanic/Latinx adults with IgAN show rapid eGFR decline and high kidney event rates in retrospective cohort
- Serenity therapy reduces symptoms and improves coping in geriatric hemodialysis patients
- Systematic review shows high CKD prevalence and undiagnosed cases among hypertensive patients in Arab countries
- ESRD patients experienced 8.7-12.9 excess deaths per 1,000 during early U.S. COVID-19 pandemic
- Phase 2a trial of dazodalibep plus belatacept shows 25% acute rejection rate in kidney transplant patients
- Hybrid machine learning model predicts CKD progression in Stage 3 adults using longitudinal data
- Case report links imported pediatric medications contaminated with diethylene glycol to acute kidney injury in Gambian children
- Meta-analysis finds higher circulating stearic acid associated with lower CKD risk in 18,193 adults
- Serial serum creatinine monitoring may detect early GFR decline above 60 mL/min before CKD stage 3
- Lixisenatide shows no effect on arterial stiffness in type 2 diabetes with chronic kidney disease
- Environmental factors predict CKDu prevalence with 85% accuracy in Sri Lankan observational study
- Observational study finds 49% AKI incidence in fulminant myocarditis patients, identifies risk factors
- Meta-analysis finds 2% mean prevalence of class 1 revascularization indications in prekidney transplant CAD screening
- Balanced salt solution in pediatric septic shock linked to lower AKI and RRT rates versus normal saline
- Survey reports on percentage of US adults with kidney disease; specific findings not provided
- Genetic testing identified positive findings in 24% of CKD patients and changed management in most cases
- Shift work associated with 43% higher odds of chronic kidney disease in meta-analysis
- Linezolid vs clindamycin shows no ICU or hospital stay difference in severe SSTIs
- Omega-3 fatty acids may reduce CRP in haemodialysis patients, but evidence is limited
- Metabolic syndrome associated with higher cardio-renal risk in kidney transplant recipients
- NGAL biomarker shows promise for AKI detection and peritoneal dialysis-related peritonitis management
- High albumin-corrected anion gap linked to increased MACE risk in CKD patients after PCI
- Standardized sonographic parameters POV and PVD show association with chronic injury in kidney transplant dysfunction
- Case report: Deep tissue massage linked to renal artery occlusion and kidney infarction in healthy man
- Xenotransplantation shows potential for end-stage kidney disease but remains experimental
- Retrospective study of semaglutide in 17 patients with type 2 diabetes and end-stage renal disease
- Case report: Liver transplant recipient on dialysis for over 10 months recovered kidney function
- TRACK trial to assess low-dose rivaroxaban for MACE in advanced CKD/dialysis patients
- Synbiotics Reduce Inflammation and Intestinal Permeability in Kidney Transplant Recipients
- Phase 2 Study Evaluates Abatacept for Kidney Transplant Recipients