Astragaloside IV significantly reduces renal fibrosis markers and serum creatinine in preclinical animal models
Astragaloside IV Shows Potential for Treating Chronic Kidney Disease
This meta-analysis of preclinical animal studies indicates that Astragaloside IV significantly reduces serum creatinine, blood urea nitrogen…
Early research in animal models suggests that Astragaloside IV may reduce key markers of kidney damage and fibrosis in chronic kidney diseas…
Gut-kidney axis drives sepsis-associated AKI, review argues for microecological and neuromodulatory therapies
New Approaches Target Gut Health to Treat Sepsis Kidney Damage
This systematic review examines the gut-kidney axis as a mechanistic driver of sepsis-associated acute kidney injury and evaluates microecol…
New research explores how targeting the gut-kidney axis could help treat and prevent kidney damage in patients with sepsis.
Four mailer types aim to increase health care proxy documentation in patients with chronic conditions
New trial plans to use mailers to help patients name proxies
This study protocol describes a factorial randomized trial of approximately 20,000 patients with cancer, congestive heart failure, or chroni…
A new study plans to see if different types of mailers can help patients with serious illnesses name a healthcare proxy.
High abdominal aortic calcification index predicts poorer cardiovascular event-free survival in patients with chronic kidney disease
High Abdominal Aortic Calcification Linked to Worse Outcomes in Kidney Disease
This meta-analysis of 1,914 patients found that high abdominal aortic calcification index (ACI) is associated with significantly worse cardi…
High levels of calcium buildup in the aorta are linked to a higher risk of heart issues and lower survival in patients with chronic kidney d…
Pegylated erythropoietin provides improved Hb stability and reduced dosing frequency in CKD-related anemia
Expert Consensus Shows Pegylated Erythropoietin Benefits Chronic Kidney Disease Patients
This expert consensus evaluates the use of pegylated erythropoietin for CKD-related anemia in India. The consensus indicates that pegylated …
A new expert consensus suggests that pegylated erythropoietin can improve hemoglobin stability and reduce dosing frequency for patients with…
CABG reduces all-cause death and repeat revascularisation risk in patients with diabetes and CKD
CABG Shows Lower Risk for Patients with Diabetes and CKD
This systematic review and meta-analysis of 10594 patients with multivessel coronary disease and multiple long-term conditions found CABG fa…
Surgery may offer better outcomes than other procedures for patients with heart disease who also have diabetes and chronic kidney disease.
Elevated Visceral Adiposity Index is associated with increased risk of diabetic kidney disease
High visceral fat levels linked to higher risk of kidney disease
This meta-analysis of 58,312 participants found that an elevated Visceral Adiposity Index (VAI) is associated with an increased risk of diab…
A large study of over 58,000 people links a specific measure of internal body fat to a higher risk of diabetic kidney disease.
AVF ligation reduces left ventricular mass index by 10.92 g/m in end-stage kidney disease
AVF Ligation Linked to Better Heart Health in Kidney Patients
This meta-analysis of 844 patients with end-stage kidney disease and high-flow arteriovenous fistulas found that AVF ligation was associated…
A review of clinical data suggests that closing certain blood vessels may improve heart structure for patients with end-stage kidney disease…
Vitamin D deficiency is associated with 33% higher odds of progression in chronic kidney disease
Vitamin D Deficiency Linked to Faster Chronic Kidney Disease Progression
This meta-analysis of observational studies indicates that vitamin D deficiency is associated with a 33% higher risk of progression in patie…
Low vitamin D levels are linked to a 33% higher risk of progression in patients with chronic kidney disease.
Pre-stenting increases FANS-UAS placement success from 80.0% to 94.8% in RIRS for kidney stones
Pre-stenting improves success rates for kidney stone surgery
This randomized controlled trial of 221 patients undergoing retrograde intrarenal surgery found that pre-stenting significantly improved FAN…
A new study shows that placing a stent before kidney stone surgery can make it easier for doctors to access stones and place necessary tools…
Exercise training increases circulating s-Klotho levels in adults with CKD and sarcopenia
Exercise Training Increases Klotho Levels in People with Kidney Disease
This meta-analysis of 893 participants evaluated the impact of various exercise modalities on s-Klotho and FGF23 levels. The analysis found …
Regular exercise training, including resistance and high-intensity intervals, may increase Klotho levels in adults with kidney disease and d…
Targeted strategies like senolytics and PFKFB3 blockers show preclinical efficacy in chronic kidney disease
New research explores how cells drive chronic kidney disease
This narrative review explores the mechanisms of necroptotic tubular epithelial cell death and glycolytic reprogramming in chronic kidney di…
Scientists identified a self-amplifying cycle of cell death and aging that drives scarring in chronic kidney disease.
Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
cGAS-STING signaling pathway activation drives inflammation, fibrosis, and functional decline in various kidney diseases
Immune pathway linked to kidney disease progression
This systematic review explores the role of the cGAS-STING signaling pathway in renal pathologies. The authors conclude that this pathway is…
A newly mapped immune pathway may drive kidney damage, opening doors for future treatments.
Gut microbiota dysbiosis and microbial metabolites impair renal function in sepsis-associated acute kidney injury
Sepsis may damage kidneys by letting gut bacteria toxins leak into the blood
This narrative review examines the role of gut microbiota dysbiosis in sepsis-associated acute kidney injury and acute kidney injury. The au…
A review suggests that sepsis changes gut bacteria, causing harmful toxins to leak and hurt kidneys in humans and animals.
Meta-analysis of sirolimus for cutaneous squamous cell carcinoma in kidney transplant recipients
Sirolimus lowers skin cancer risk in kidney transplant patients
This meta-analysis of four randomized trials in kidney transplant recipients with prior cutaneous squamous cell carcinoma found that switchi…
A review of studies shows switching to sirolimus can cut skin cancer rates, but it may cause more side effects.
Review of environmental exposures in agricultural communities with chronic kidney disease of unknown cause
New research hunts the hidden causes of kidney disease in farming communities
This publication is a review examining potential environmental exposures in agricultural communities in Central America and South Asia. The …
A new study hunts for the hidden causes of kidney disease in farming communities across Central America and South Asia.
Oral beraprost extends median survival in dogs with IRIS stage 2 chronic kidney disease compared to historical controls
Beraprost Adds Years to Dogs’ Lives with Early Kidney Disease
This prospective clinical study evaluated oral beraprost in dogs with naturally occurring IRIS stage 2 chronic kidney disease.
Dogs with early kidney disease who took a certain medication lived more than five times longer than those who didn’t — and vets are taking n…
Narrative review supports SGLT-2i use in cardiovascular-kidney-metabolic syndrome
New Treatment Shifts How We Fight Heart, Kidney, and Diabetes Damage
This narrative review summarizes evidence on SGLT-2 inhibitors for patients with stages 2–4 cardiovascular-kidney-metabolic syndrome.
Maria, 58, has type 2 diabetes and high blood pressure.
Systematic Review Examines Therapeutic Strategies Targeting Renal ELD in Kidney Diseases
Kidney Damage May Start With Fat in the Wrong Places
This systematic review summarizes mechanisms and therapeutic strategies targeting renal ELD across kidney diseases, including diabetic and…
This research explains how fat in the wrong kidney cells causes harm, opening new paths for prevention and treatment.
Body roundness index shows significant association with metabolic syndrome but constrained predictive ability for other CKM outcomes
A Simple Body Measurement May Reveal Your Hidden Health Risk
This systematic review and meta-analysis of 93 observational studies from 13 countries evaluated the body roundness index (BRI) against conv…
A simple math formula using your height and waist size may help doctors catch silent health problems long before they turn serious.
Higher cumulative inflammatory-metabolic index linked to increased risk of rapid kidney function decline in older adults
A Simple Blood Test May Now Predict Your Kidney Health Years Earlier
A cohort study of 6,888 middle-aged and older adults found that each one-unit increase in cumulative C-reactive protein-triglyceride glucose…
A simple blood test combining inflammation and sugar levels can predict rapid kidney decline years before serious damage occurs in adults.
Modified cardiometabolic index predicts mortality in adults with cardiovascular-kidney-metabolic syndrome better than traditional indices
New Score Predicts Heart and Kidney Risk Better Than Old Tests
This prospective cohort study of 5,189 adults with cardiovascular-kidney-metabolic syndrome assessed the modified cardiometabolic index (MCM…
A new health score predicts heart and kidney failure risk better than standard blood tests, revealing hidden dangers in millions of patients…
Biological age acceleration linked to faster progression from cardiovascular-kidney-metabolic disease to dementia
Your Body Might Be Older Than Your Birthday Says
A prospective cohort study of 433,911 UK Biobank participants found biological age acceleration was associated with increased risk of transi…
People whose biological age ran ahead of their calendar age moved faster through a chain of chronic diseases that ended in dementia or earli…
Higher BUN/Cr ratio linked to increased mortality in older patients with sepsis-associated AKI
A Simple Blood Test Ratio Could Predict Survival in Severe Infections
A retrospective cohort study of 764 patients aged ≥50 years with sepsis-associated AKI found each 1-unit increase in BUN/Cr ratio was associ…
A simple blood test ratio linked to kidney failure in severe infections now helps doctors predict which patients face higher survival risks.
Questions about Chronic Kidney Disease
Does taking NSAIDs during pregnancy increase the risk of kidney disease in my child?
A large review of seven studies found that taking NSAIDs during pregnancy is linked to a higher risk of kidney disease in children, with the risk increasing when used in the second and third trimesters.
Full answer →Are there new guidelines for kidney cancer based on recent 2025 trials?
Yes, the 2025 EAU guidelines update kidney cancer care with new recommendations on stereotactic body radiotherapy, adjuvant therapy, and systemic treatments for clear-cell and hereditary RCC.
Full answer →How can artificial intelligence help patients with kidney cancer in surgery?
Artificial intelligence helps kidney cancer patients by improving tumor detection on scans, planning robotic surgeries, and predicting surgical outcomes to reduce complications.
Full answer →Are complication risks for kidney stone surgery higher in elderly patients?
Yes, elderly patients have higher risks of sepsis after PCNL, but overall complication rates are similar to younger patients for most kidney stone surgeries.
Full answer →Do complement pathways play a role in kidney diseases affecting my transplant?
Yes, complement pathways are involved in kidney transplant rejection, including antibody-mediated rejection, and may be targeted for therapy.
Full answer →What mechanisms link obesity to inflammation in chronic kidney disease?
Obesity fuels kidney inflammation through adipose tissue dysfunction, lipotoxicity, altered secretion of inflammatory factors, and gut-derived uremic toxins, creating a vicious cycle that worsens chronic kidney disease.
Full answer →Can layered data models help doctors find my risk for diabetic kidney disease earlier?
Yes, layered data models that combine clinical, lab, medication, and social data can help doctors detect diabetic kidney disease risk earlier than traditional methods alone.
Full answer →Can a machine learning model find hidden diabetic kidney disease while I am hospitalized?
Yes, a machine learning model using routine hospital data can detect hidden diabetic kidney disease, even when standard tests appear normal.
Full answer →All Chronic Kidney Disease Articles
- Astragaloside IV significantly reduces renal fibrosis markers and serum creatinine in preclinical animal models
- Gut-kidney axis drives sepsis-associated AKI, review argues for microecological and neuromodulatory therapies
- Four mailer types aim to increase health care proxy documentation in patients with chronic conditions
- High abdominal aortic calcification index predicts poorer cardiovascular event-free survival in patients with chronic kidney disease
- Pegylated erythropoietin provides improved Hb stability and reduced dosing frequency in CKD-related anemia
- Elevated Visceral Adiposity Index is associated with increased risk of diabetic kidney disease
- CABG reduces all-cause death and repeat revascularisation risk in patients with diabetes and CKD
- AVF ligation reduces left ventricular mass index by 10.92 g/m in end-stage kidney disease
- Vitamin D deficiency is associated with 33% higher odds of progression in chronic kidney disease
- Pre-stenting increases FANS-UAS placement success from 80.0% to 94.8% in RIRS for kidney stones
- Targeted strategies like senolytics and PFKFB3 blockers show preclinical efficacy in chronic kidney disease
- Exercise training increases circulating s-Klotho levels in adults with CKD and sarcopenia
- Elevated glucose, chloride, and anion gap levels are associated with increased risk of acute kidney injury
- Periodontal conditions and plaque index correlate with lower oral health-related quality of life in ESRD patients
- Salivary urea, creatinine, calcium, and pH are significantly higher in patients with chronic kidney disease
- MDS patients have 6.2 times higher cardiovascular disease prevalence than the general population
- Dysregulated tryptophan metabolism drives neurocognitive complications in approximately 40% of patients with chronic kidney disease
- Protein-energy wasting prevalence reaches 47.0% among patients with chronic kidney disease in Africa
- Oral microbiome dysbiosis is observed in children and adolescents with chronic kidney disease
- Intranasal desmopressin reduces bleeding risk in CKD patients during non-surgical procedures
- Star fruit-infused liquor consumption can cause secondary oxalate nephropathy and acute kidney injury
- cGAS-STING pathway activation drives inflammation, fibrosis, and podocyte injury in various kidney diseases
- Natural products like polysaccharides and TCM formulas may modulate gut microbiota to protect renal function
- Targeting cannabinoid receptors may modulate CKD and AKI progression in animal models
- Elevated syndecan-1 levels correlate with severity and poor outcomes in patients with sepsis
- Machine learning models achieve a pooled AUC of 0.834 for predicting acute kidney injury occurrence
- Reduced-dose daratumumab and bortezomib may achieve partial renal remission in CyBorD-refractory PGNMID
- RIT1 p.Thr83Pro variant is associated with severe neonatal outcomes in Noonan syndrome cases
- Dietary fiber reduces indoxyl sulfate by 0.13 mg/dL in humans with CKD
- Sacubitril/valsartan associated with improved renal outcomes in patients with heart failure
- MASLD is associated with higher CKD prevalence and accelerated renal impairment progression
- CKD-MBD medication titration is associated with serum calcium, phosphorus, and parathyroid hormone levels
- Ivonescimab-containing chemoimmunotherapy can trigger rare ADAMTS13 inhibitor-positive immune thrombotic thrombocytopenic purpura
- Chronic kidney disease is associated with increased plaque, calculus, and gingival inflammation
- Combined nutrition and exercise improves physical performance in patients on hemodialysis
- Finerenone reduces UACR by 25% in adults with type 1 diabetes and CKD
- Mitochondrial metabolic reprogramming and epigenetic modifications drive bidirectional regulation in renal tubular epithelial cells
- Insulin resistance and hyperinsulinemia drive bidirectional links between biological aging and age-related chronic diseases
- Natural products offer multi-target renoprotective effects for metabolic, inflammatory, and oxidative stress pathways
- Chronic kidney disease prevalence of 13.7% identified across 19 African countries
- Frailty associated with higher odds of cognitive impairment in patients with chronic kidney disease
- GLP-1 receptor agonists and tirzepatide provide cardiovascular benefits across multiple clinical scenarios
- Herbal Medicinal Bath shows stable efficacy for chronic kidney disease-associated pruritus in network meta-analysis
- PPI Guided Fluid Resuscitation Reduces Incidence of Acute Skin Failure in Critically Ill Patients
- Inflammation and immune dysregulation drive chronic kidney disease progression and associated tissue remodeling
- Staged PCI reduces severe kidney injury risk after TAVR in aortic stenosis and CAD
- Finerenone Efficacy and Safety in Patients with Chronic Kidney Disease and Glomerular Disease
- Vitamin D supplementation shows low certainty reductions in urinary markers for diabetic kidney disease
- Unified cardiometabolic disease framework links T2DM, ASCVD, HFpEF, MASLD, hypertension, and CKD via shared pathophysiology
- Age, male sex, low BMI, and comorbidities like diabetes are significant risk factors for sepsis incidence
- m6A modification regulates renal tubular epithelial cell fate and inflammatory responses in acute kidney injury
- Mediterranean and DASH diets consistently support mitigation of cardiometabolic risk in metabolic syndrome patients
- Immune checkpoint inhibitors are associated with acute kidney injury and multi-organ immune-related adverse events
- PCSK9 monoclonal antibodies show promise for renal benefit in diabetic kidney disease
- Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases
- Renal vascular variations do not compromise long-term outcomes in patients with complex anatomy
- Lipid metabolism disorders drive podocyte injury and extracellular matrix deposition in diabetic kidney disease
- Serum cystatin C shows consistent increase in cats with CKD while urinary cystatin B elevates in dogs
- KidneyTIME digital intervention improves knowledge and listing behaviors but not donor inquiries in kidney transplant candidates
- Inclisiran reduces LDL cholesterol by up to 54.7% in patients with atherosclerotic cardiovascular disease
- Dapagliflozin reduces proteinuria and blood pressure but does not improve eGFR in CAD patients
- Higher Triglyceride-Glucose index is associated with increased risk of albuminuria in chronic kidney disease
- Higher Systolic Blood Pressure Time in Target (SBP TTR) associated with 10% lower risk of poor kidney outcomes
- Children with posterior urethral valves and adverse prognostic features have 1.44 times higher CKD risk
- Canagliflozin mitigates increased cardiovascular risk from low-normal sodium intake in type 2 diabetes and CKD
- Pooled prevalence of diabetic kidney disease among Brazilian adults is 27.06% across 46 studies
- Semaglutide significantly reduces BMI and improves hypertension control in patients with obesity and CKD
- Finerenone reduces mortality and heart failure risk (HR 0.644) in post-AMI patients
- Post-translational modifications represent a critical target for precise molecular intervention in diabetic kidney disease
- Digital health technologies offer varying levels of clinical readiness for managing sarcopenia in hemodialysis patients
- Continuous renal replacement therapy may support metabolic and circulatory stability in preterm infants with AKI
- Programmed cell death pathways form a spatiotemporally regulated network driving tubular damage in renal IRI
- Machine learning models show high diagnostic accuracy for predicting pediatric cardiac surgery associated acute kidney injury
- Peripheral nerve blocks reduce 24-hour morphine use by 16.20 mg in kidney transplant recipients
- Active stone-directed intervention reduces odds of composite recurrence and surgery for asymptomatic kidney stones
- Roxadustat increases odds of vascular access thrombosis and all-cause mortality in patients with chronic kidney disease
- Ambulatory hypertension in pediatric chronic kidney disease patients increases risk of left ventricular hypertrophy
- Cystatin C shows good diagnostic performance with an AUC of 0.88 for early detection of SA-AKI
- Risk-adapted HLA delisting and imlifidase enable deceased-donor kidney transplantation for highly sensitized candidates
- Semaglutide reduces risk of kidney decline or death in type 2 diabetes and CKD
- Gut microbiota dysbiosis and microbial metabolites impair renal function in sepsis-associated acute kidney injury
- Semaglutide use may be associated with kidney damage in 20 cases across 18 studies
- Jinlida Granule reduces serum creatinine and HbA1c in diabetic kidney disease patients across a meta-analysis
- Steroid avoidance may reduce death and diabetes after kidney transplant but raises rejection risk
- ILC dysregulation and gut microbiota dysbiosis may drive kidney disease via the microbiota-gut-kidney axis
- Kidney transplantation reduces left-ventricular mass index by 22 g/m² in end-stage kidney disease
- Pulsed-field ablation shows no significant AKI difference versus radiofrequency ablation in AF
- Fluoroless ultrasound-guided techniques lower complications in percutaneous nephrolithotomy with equivalent stone-free rates
- ECIRS triples stone-free odds versus PCNL in large kidney stones, meta-analysis finds
- Chronic kidney disease linked to shorter leukocyte telomere length in meta-analysis
- Education and behavior interventions reduce burden for CKD caregivers in a systematic review
- Acute kidney function decline timing predicts mortality and heart failure outcomes in hospitalized patients
- Gut dysbiosis contributes to CKD complications via interconnected pathways, though mechanistic validation remains incomplete
- Exosomes show promise as biomarkers and therapeutic vectors in diabetic complications
- Cerivastatin best for total cholesterol, simvastatin for LDL-C in DKD with hyperlipidemia
- Nutritional vitamin D reduces CRP and improves albumin in maintenance hemodialysis patients
- Pyrethroid insecticide exposure linked to acute kidney injury in a 55-year-old male
- Case report confirms X-linked Alport syndrome diagnosis in a young girl with family history
- Clinical and laboratory abnormalities linked to higher mortality in malaria patients with acute kidney injury
- Complement activation in acute kidney injury a convergent mechanism
- Systematic review and meta-analysis links prenatal NSAIDs to higher kidney disease risk in children
- Systematic review and meta-analysis of prediction models for diabetic kidney disease progression to ESRD
- Systematic review and meta-analysis on FGF23 levels in diabetic kidney disease
- Mini review of Explainable AI for kidney stone segmentation in resource-constrained settings
- Narrative review of salvianolic acids for kidney disease pharmacokinetics and anti-fibrotic activity
- Narrative review examines ureteroscopy with negative-pressure suction sheath for kidney and ureteral stones
- Meta-analysis finds lower bleeding risk with apixaban and rivaroxaban vs VKAs in dialysis patients with AF
- Narrative review explores gut-kidney axis in chronic kidney disease progression
- Meta-analysis finds SGLT2 inhibitors reduce cardiac arrest risk in CKD patients
- Combining finerenone with SGLT2 inhibitors lowers mortality and cardiovascular events in diabetic chronic kidney disease patients
- Meta-analysis links acute kidney injury to increased stroke, delirium, and dementia risk
- Narrative review of lung, breast, liver, and kidney cancer evidence
- Case report suggests hemorrhagic fever with renal syndrome may trigger secondary hyperparathyroidism
- Digital decision support tools showed parallel improvements with no between-group differences in kidney outcomes among adults with chronic kidney disease in Chinese primary care centers
- HIF-PHIs alter lipid profiles in CKD patients but show no cardiovascular mortality difference
- Pentoxifylline Improves Kidney Function and Reduces Inflammation in CKD
- Complication risks in elderly patients undergoing percutaneous nephrolithotomy compared to younger populations
- CABG versus PCI in high-risk coronary revascularisation patients shows mixed outcomes over 5 years
- Arterioarterial grafts show high patency in hemodialysis patients
- Systematic review links gestational diabetes to higher maternal CKD risk in large cohort analysis
- MUSKARDIA shows protective trend in stable CAD with reduced eGFR
- Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients
- Meta-analysis shows associations between hypothyroidism and increased chronic kidney disease prevalence
- Scoping review finds SGLT2 inhibitors show kidney protection in IgA nephropathy
- RIRS with TFLLT shows similar stone-free rates to PNL for 20-30 mm kidney stones in adults
- Hypophosphatemia during KRT linked to fewer ventilator-free days in critically ill patients
- Kidney-directed SBRT shows modest renal function decline in inoperable patients
- Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients
- Systematic review and meta-analysis of health coaching interventions in chronic kidney disease patients
- Meta-analysis finds GLP-1RA plus SGLT2i reduces UACR in type 2 diabetes with kidney disease
- Systematic review and meta-analysis of MRAs in dialysis patients shows reduced nonfatal CVD events but elevated hyperkalemia and gynecomastia risks
- Permanent night shift work associated with increased chronic kidney disease risk in UK Biobank participants
- Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
- Systematic Review Links Lysosomal Pathways to Autoimmune Kidney Disease Progression
- Machine learning model identifies RLS in ESRD patients with AUC 0.791
- Mini Review Covers Complement Pathways in Kidney Diseases and Injuries
- Narrative review discusses renal risks in inflammatory bowel disease patients
- Higher sdLDL-C Linked to Lower Kidney Stone Risk in Two Cohorts
- Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
- White blood cell indicators predict acute kidney injury in critically ill advanced colorectal cancer patients
- Higher TyG index linked to increased renal function progression risk in patients with CKD stages 3–4
- Observational study links cutaneous microvascular function to chronic kidney disease severity
- Individual-participant data meta-analysis shows blood-pressure lowering reduces cardiovascular risk in CKD and non-CKD populations
- Machine learning model improves early detection of occult diabetic kidney disease in hospitalized patients
- Oral beraprost extends median survival in dogs with IRIS stage 2 chronic kidney disease compared to historical controls
- Circulating SVEP1 Protein Associated With Major Adverse Cardiovascular Events in Hemodialysis Patients
- Cross-sectional study links declining nephron number to CKD stage in diabetic nephropathy
- Meta-analysis of dapagliflozin for renal outcomes in type 2 diabetes and CKD
- High-altitude ICU study finds 21% AKI incidence in neurocritical patients
- Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
- Narrative review supports SGLT-2i use in cardiovascular-kidney-metabolic syndrome
- Systematic review and meta-analysis shows dapagliflozin increases hemoglobin in chronic kidney disease patients
- Systematic review and meta-analysis shows exercise improves depression and quality of life in hemodialysis patients
- Observational review of layered data models improves DKD risk detection in type 2 diabetes cohorts
- Systematic review of anti-IL-5 biologics in hypereosinophilic syndrome kidney disease reports low certainty evidence
- Inflammatory indices associated with increased chronic kidney disease risk in coronary artery disease cohort
- Systematic review examines oral microbiota associations with chronic kidney disease and early childhood caries
- Flexible suction sheath outperforms conventional sheath in renal stone surgery
- Conservative fluid management shows no difference in tissue perfusion or kidney injury in critically ill adults
- Preclinical analysis of gnomAD and ClinVar databases on ADPLD variant frequencies
- Dyslipidemia linked to poorer renal survival in primary IgA nephropathy patients
- Pilot RCT tests digital inclusion intervention for adults with chronic kidney disease
- CRRT after heart transplantation linked to preoperative hemoglobin and VIS score in cohort study
- Chemotherapy-related renal injury incidence and risk factors in patients with malignant tumors
- Updated PIRCHE-T2 model improves dnDSA risk stratification in kidney transplant recipients
- 24-hour diastolic BP variability linked to renal decline in diabetic kidney disease
- O. vulgatum consumption linked to rhabdomyolysis and acute kidney injury in 10 patients
- Single-centre observational study on hemodialysis duration and outcomes in end-stage renal disease
- Systematic Review Examines Therapeutic Strategies Targeting Renal ELD in Kidney Diseases
- Meta-analysis of nutrition education in adult dialysis patients shows improved knowledge and quality of life
- Review summarizes therapeutic strategies targeting cGAS-STING-macrophage axis for renal fibrosis and chronic kidney disease
- FluxPro-DKD fusion model integration shows higher AUC for early-stage DKD detection in type 2 diabetes
- Elevated TyG index linked to renal deterioration in CKD and hypertensive cohorts
- Meta-analysis links chronic kidney disease to higher mortality after intracerebral hemorrhage
- Meta-analysis of 24 animal studies shows emodin reduces kidney injury markers in preclinical models
- Gastrointestinal complications in cardiac surgery patients are linked to high mortality and multiorgan failure
- Minimum immunobiology packages may improve kidney transplant safety and equity in low- and middle-income settings
- Cross-Sectional Analysis of Protective Foot Sensation and Complications in 387 Type 2 Diabetes Patients
- Atherogenic index of plasma shows non-linear association with mortality in diabetic AKI patients
- Cryopreserved venous allografts increased cold ischemia time in living-donor kidney transplant recipients
- Body roundness index shows significant association with metabolic syndrome but constrained predictive ability for other CKM outcomes
- Total IgG Concentration Linked to Anemia in Hemodialysis Patients
- Multimodal AI applications in urologic oncology for prostate, bladder, and kidney cancers
- Narrative review suggests coordinated care models may strengthen European primary health care systems
- Physical exercise reduces all-cause mortality and improves outcomes in chronic kidney disease patients
- Retrospective analysis of PEW diagnosis prevalence and correlates in children with CKD stages 3-5D
- Thiamin supplementation associated with reduced mortality in septic shock patients
- Carotid plaque measures predict coronary heart disease in CKD patients
- Proenkephalin A levels show no correlation with kidney or cardiac markers in hemodialysis patients
- NIID patients with kidney injury show higher immune markers compared to those without kidney injury
- Meta-analysis identifies risk factors for diabetic kidney disease in Asian patients with type 2 diabetes
- Cross-sectional study links CKD, sarcopenia, and undernutrition to CVD history in older Japanese adults
- Telemonitoring in adult kidney transplant recipients improved patient satisfaction and access to care
- Higher cumulative inflammatory-metabolic index linked to increased risk of rapid kidney function decline in older adults
- Network meta-analysis of novel antidiabetic drugs in T2DM with CKD shows sotagliflozin, empagliflozin, and semaglutide rank highest for cardiovascular and renal outcomes
- Oral semaglutide reduces composite heart failure outcomes in patients with type 2 diabetes and heart failure history
- Antimicrobial stewardship bundle improved perioperative antibiotic protocol adherence in oncourology surgeries
- Genetic correlation between kidney function and Alzheimer disease is absent in European and African ancestry cohorts
- CI-AKI in ACS patients undergoing PCI was associated with a 4.7-fold increased hazard of death within 90 days
- Systematic review of 2025 RCTs identifies new standards of care across genitourinary cancers