N/A N=11 Treatment

Acute Cardiovascular and Metabolic Effects of Exercise Training in Individuals With Insulin Resistance

Insulin Resistance

Bottom Line

View on ClinicalTrials.gov: NCT00954109 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2015

Primary outcome: Primary: Insulin Sensitivity After 5-7 Days of Exercise — 3; 2.5 index score — p=<0.05

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Exercise (Behavioral)
Age: Adult, Older Adult · 30+ yrs
Sex: All
Sponsor: US Department of Veterans Affairs
Primary completion: Dec 2010

Outcome Measures

Outcome	Result	p-value
PRIMARY Insulin Sensitivity After 5-7 Days of Exercise	3; 2.5	<0.05 sig
PRIMARY Blood Flow in Response to Oral Glucose Tolerance Tests	0; 40	<0.05 sig

Summary

The overall aim of the project is to determine whether or not exercise influences cardiovascular or nervous responses to meal ingestion in individuals with insulin resistance or type 2 diabetes.

Eligibility Criteria

Inclusion Criteria

Insulin resistant: diagnosed with pre-diabetes or fasting blood glucose >/= 100 mg/dL
T2D: diagnosed by primary care physician
BMI: less than 43 kg/m2
Age: 30-65

Exclusion Criteria

Smoking
Insulin use (other than once daily)
Underlying conditions that limit ability to exercise safely
Recent weight gain or loss (>5% of body weight in 3 months)
Physically active (>30 min aerobic exercise, 2 d/wk)
Recent ( 10%)
Advanced retinopathy or neuropathy
Pregnancy

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00954109). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.