N/A
N=194
Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons
Obesity
Bottom Line
View on ClinicalTrials.gov: NCT00960414 ↗Enrolled (actual)
194
Serious AEs
0.0%
Results posted
Feb 2024
Primary outcome: Primary: Change in Weight From Baseline to 18 Months — -5.0; -3.2 kg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- SHINE (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of California, San Francisco
- Primary completion
- Aug 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Weight From Baseline to 18 Months |
-5.0; -3.2 | — |
| SECONDARY Fat Distribution |
-4.8; -3.6 | — |
| SECONDARY Insulin Sensitivity |
-.011; 0.50 | — |
| SECONDARY Change in Perceived Stress From Baseline to 18 Months |
-1.03; -0.11 | — |
| SECONDARY Change in Positive Emotions Subscale of the Differential Emotions Scale |
2.49; -0.21 | — |
| SECONDARY Stress Hormones |
— | — |
| SECONDARY Autonomic Nervous System Function |
— | — |
| SECONDARY Adipocyte Activity |
— | — |
| SECONDARY Influenza Vaccine Response |
— | — |
Summary
The purpose of this study is to compare two approaches to a diet and exercise-based weight loss program.
Eligibility Criteria
Inclusion Criteria
- Age 18+ years old
- BMI > 30-45
- Waist circumference > 102 cm (men) or > 88 cm (women)
- Live in San Francisco Bay Area and able to attend more than 16 classes and up to 12 assessment visits in San Francisco over an 18 month period
Exclusion Criteria
- Inability to provide informed consent
- Age 4mU/mL (or the upper limit of normal reference defined by the lab doing the assay)
Data sourced from ClinicalTrials.gov (NCT00960414). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.