N/A
Completed N=71
Pulmonary Rehabilitation in Patients Before Lung Transplantation (LTx)
Chronic Obstructive Pulmonary Disease · Pre-Lung-Transplantation · Hypercapnia · Respiratory Insufficiency
Source: ClinicalTrials.gov NCT00962078 ↗
Enrolled (actual)
71
Serious AEs
0.0%
Results posted
Sep 2019
Primary outcomePrimary: Effects of a Multimodal Pulmonary Rehabilitation Program on 6 Minute Walking Distance (6MWD) — 35; 36 meter
Summary
The purpose of this study is to study the effects of a complex pulmonary rehabilitation program on mobility measured by 6 minute walking distance (6MWD) and physical activity, measured via Dynaport and Actibelt Aktivitätsmonitor, dyspnoea (VAS), quality of life (HRQL (SF36, EuroQul)), anxiety and depression (HADS)and PaCO2-behavior under physical activity.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Effects of a Multimodal Pulmonary Rehabilitation Program on 6 Minute Walking Distance (6MWD) |
35; 36 | — |
| SECONDARY Dyspnoea During Exercise Measured on the Borg Scale |
6.2; 7.2 | — |
Eligibility Criteria
Inclusion Criteria
- pre-LTx (listed for lung-transplantation or currently undergoing evaluation)
- COPD Stadium IV GOLD
- α-1-Antitrypsin-deficiency-Emphysema
- respiratory Insufficiency
- oxygen therapy (LTOT)
Exclusion Criteria
- serious Exacerbation (Symptoms longer than three days, change of therapy, e.i. antibiotics, steroids) during the last four weeks before rehabilitation
- clinical signs of manifest heart insufficiency
- acute coronar syndrome
- left heart insufficiency(EF < 40%)
- missing Compliance
Data sourced from ClinicalTrials.gov (NCT00962078). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.