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N/A N=71 Randomized Treatment

Pulmonary Rehabilitation in Patients Before Lung Transplantation (LTx)

COPD · Pre-Lung-Transplantation · Hypercapnia · Respiratory Insufficiency

Enrolled (actual)
71
Serious AEs
0.0%
Results posted
Sep 2019
Primary outcome: Primary: Effects of a Multimodal Pulmonary Rehabilitation Program on 6 Minute Walking Distance (6MWD) — 35; 36 meter

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
continuous endurance training (Other); interval training (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Schön Klinik Berchtesgadener Land
Primary completion
Oct 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Effects of a Multimodal Pulmonary Rehabilitation Program on 6 Minute Walking Distance (6MWD)
35; 36
SECONDARY
Dyspnoea During Exercise Measured on the Borg Scale
6.2; 7.2

Summary

The purpose of this study is to study the effects of a complex pulmonary rehabilitation program on mobility measured by 6 minute walking distance (6MWD) and physical activity, measured via Dynaport and Actibelt Aktivitätsmonitor, dyspnoea (VAS), quality of life (HRQL (SF36, EuroQul)), anxiety and depression (HADS)and PaCO2-behavior under physical activity.

Eligibility Criteria

Inclusion Criteria

  • pre-LTx (listed for lung-transplantation or currently undergoing evaluation)
  • COPD Stadium IV GOLD
  • α-1-Antitrypsin-deficiency-Emphysema
  • respiratory Insufficiency
  • oxygen therapy (LTOT)

Exclusion Criteria

  • serious Exacerbation (Symptoms longer than three days, change of therapy, e.i. antibiotics, steroids) during the last four weeks before rehabilitation
  • clinical signs of manifest heart insufficiency
  • acute coronar syndrome
  • left heart insufficiency(EF < 40%)
  • missing Compliance
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00962078). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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