N/A
Completed N=90
Intra-articular Glucocorticoid Treatment of the Elbow
Source: ClinicalTrials.gov NCT00972530 ↗Enrolled (actual)
90
Serious AEs
0.0%
Results posted
Nov 2009
Primary outcomePrimary: Relapse of Arthritis — 8; 13; 44; 46 participants
Summary
BACKGROUND: Intra-articular glucocorticoid injections are frequently used to relieve symptoms of arthritis. Postinjection rest has been shown to improve the outcome of knee joint injections, but not for wrist injections. Consequently, different joints respond differently on postinjection regimens.
OBJECTIVES: To investigate whether better treatment results might be achieved of post-injection rest following intra-articular glucocorticoid treatment for elbow synovitis.
METHODS: 90 patients with rheumatoid arthritis (RA) and elbow synovitis were treated with 20 mg intra-articular triamcinolone hexacetonide and randomised to either a 48 hour immobilisation in a triangular sling (n=46) or normal activity without restrictions (n=44). Primary endpoint was relapse of synovitis. In addition, pain, function according to a self assessment questionnaire (PREE) and range of movement were followed for six months.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Relapse of Arthritis |
8; 13; 44; 46; 43; 43 | — |
Eligibility Criteria
Inclusion Criteria
- Rheumatoid arthritis, and
- Clinical signs of elbow synovitis
Exclusion Criteria
- Patients in function class 4 according to Steinbrocker as well as patients with oral glucocorticoid treatment corresponding to more than 7.5 mg prednisolone or intra-articular treatment in the joint the past three months
Data sourced from ClinicalTrials.gov (NCT00972530). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.