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N/A N=60 Randomized Health Services Research

Safe Critical Care: Testing Improvement Strategies

Central Line-associated Bloodstream Infection (CLABSI) · Ventilator Associated Pneumonia

Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Jan 2016
Primary outcome: Primary: CLABSI and VAP Rates — 1.84; 2.42; 2.24; 2.47 events/1000 device days — p=<.05

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Collaborative Group (Behavioral); Tool Kit (Behavioral)
Age
Pediatric, Adult, Older Adult · 1+ yrs
Sex
All
Sponsor
Vanderbilt University
Primary completion
Apr 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
CLABSI and VAP Rates
1.84; 2.42; 2.24; 2.47; 2.28; 2.54 <.05 sig
SECONDARY
Access of Tools and Use of Quality Improvement Strategies
61; 49; 56; 30; 69; 54 <05

Summary

One group of hospitals participated in a collaborative approach for healthcare quality improvement while another group was provided only a tool kit. The investigators' objective was to determine if the Collaborative would perform better at preventing central line-associated bloodstream infections (CLABSI) and ventilator-associated pneumonias (VAP). Hospitals were randomized to the Tool Kit or Collaborative conditions. The investigators' study evaluated the effects on care processes and outcomes of a multi-institutional quality improvement initiative focused on preventing hospital associate infections. The investigators' hypothesis was that the strategies for implementing safe critical care practice will differ in level of achievement whereby the Collaborative group will perform better than the Tool Kit group. The outcome measure comprised clinical event rates and an index of safe practices that represent a bundling of key process measures related to evidence-based practices for preventing catheter-related blood-stream infections and ventilator-associated pneumonia in the intensive care unit.

Eligibility Criteria

Inclusion Criteria

  • Medical centers with at least one adult or pediatric ICU.
  • Medical centers within the Hospital Corporation of America (HCA) were eligible for enrollment.

Exclusion Criteria

  • Nonresponse to invitation to participate in our Safe Critical Care Initiative.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00975923). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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