N/A N=32 Randomized Single-blind Treatment

Intradialytic Progressive Resistance Training for Maintenance Haemodialysis Patients

Chronic Kidney Disease

Bottom Line

View on ClinicalTrials.gov: NCT01007838 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2011

Primary outcome: Primary: Muscle Cross Sectional Area — 3.24; -4.62; 4.39; -0.15 cm2 — p=0.30

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Progressive resistance training programme (Other); Sham exercise (Other); Progressive resistance training (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Bangor University
Primary completion: Oct 2011

Outcome Measures

Outcome	Result	p-value
PRIMARY Muscle Cross Sectional Area	3.24; -4.62; 4.39; -0.15	0.30
SECONDARY Muscle Strength	—	—

Summary

The purpose of this study is to investigate the effects of a 12 week progressive resistance training during haemodialysis on muscle quantity and physical functioning in chronic kidney disease patients receiving maintenance haemodialysis. It is hypothesised, based on previous literature involving similar resistance training protocols in other catabolic conditions, that the resistance training will result in a significant increase in muscle quantity as well a physical function.

Eligibility Criteria

Inclusion Criteria

Chronic kidney diseases stage five requiring maintenance hemodialysis.

Exclusion Criteria

Patients who have been receiving dialysis for less than 3 months;
Are under the age of 18years;
Have medical contradictions to participate in the exercise programs;
Any uncontrolled medical condition which does not allow participation in exercise;
Have known neuro-muscular disorders;
Have any other uncontrolled medical condition, including pregnancy;
Are not independently ambulant for 50 m;
Have received anabolic intervention, or had catabolic conditions within the last 3 months;
Have a cardiac pacemaker or other unsuitable implanted device for magnetic resonance;
Are vulnerable to heat stress;
Or are unable to give consent.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01007838). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.