Phase 4 N=123 Randomized Quadruple-blind Treatment

Metoclopramide Versus Ketorolac for Tension-type Headache

Headache

Bottom Line

View on ClinicalTrials.gov: NCT01011673 ↗

Enrolled (actual)

123

Serious AEs

0.0%

Results posted

Dec 2012

Primary outcome: Primary: Change in Pain Score — 3.8; 5.1 units on a scale

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: Metoclopramide (Drug); Ketorolac (Drug)
Age: Adult · 21+ yrs
Sex: All
Sponsor: Montefiore Medical Center
Primary completion: Sep 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Pain Score	3.8; 5.1	—
SECONDARY Satisfaction Scores	45; 53	—

Summary

Occasionally, episodic tension-type headache may be severe enough to require an emergency department (ED) visit. The purpose of this study is to compare two commonly used medications to see which is better for tension type headache. Patients who present to the ED with an acute tension-type headache requiring treatment with injectable medication will be randomized to metoclopramide or ketorolac.

Eligibility Criteria

Inclusion Criteria

Acute tension type headache

Exclusion Criteria

Contraindications to investigational medications
Secondary cause of headache

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01011673). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.