N/A
N=513
The Darlington Retrospective Outpatient Study
Heart Failure
Bottom Line
View on ClinicalTrials.gov: NCT01013883 ↗Enrolled (actual)
513
Serious AEs
—
Results posted
Mar 2014
Primary outcome: Primary: All Cause Mortality — 163; 118 participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- County Durham and Darlington NHS Foundation Trust
- Primary completion
- Aug 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY All Cause Mortality |
163; 118 | — |
| SECONDARY Cardiovascular Mortality |
113; 51 | — |
| SECONDARY Admission to Hospital for Any Cause |
189; 158 | — |
Summary
Having heart failure means the heart is unable to pump blood around the body effectively. This reduces life expectancy and hinders normal daily activities. Heart failure affects about one million people in the UK; it is a major cause of death but it is often undetected and under-treated. If diagnosed and treated properly, the symptoms of heart failure can be well controlled and the length and quality of life can be improved.
Two drugs (called ACE-inhibitors and beta-blockers) help patients to live longer and suffer fewer consequences of heart failure. These drugs should be offered to all patients although this does not happen consistently for a variety of reasons. Doctors specialising in heart failure may help patients make better informed decisions about treatments and other aspects of care.
The purpose of this research is to explore the diagnosis, management and outcome of patients with heart failure who are referred to the one stop diagnostic heart failure clinic between Jan 2002 and Dec 2007. This study will provide vital information about diagnosis, initiation and titration of evidence based medication in the hospital, their follow in the primary care and subsequent patient outcome in terms of mortality.
Eligibility Criteria
Inclusion Criteria
- 18 years and over attending heart failure clinic between 01/01/2002- 31/12/07
Exclusion Criteria
- less than 18 years.
Pregnant females
Data sourced from ClinicalTrials.gov (NCT01013883). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.