N/A
Completed N=208
Mindfulness to Improve Elders' Immune and Health Status
Stress, Psychologic
Source: ClinicalTrials.gov NCT01027780 ↗
Enrolled (actual)
208
Serious AEs
0.0%
Results posted
Aug 2014
Primary outcomePrimary: IgG Anti-KLH Antibody Response Post-treatment — 0.172; 0.104 OD 405 nm — p=.007
Summary
The purpose of the study is to better understand effects of the Mindfulness-Based Stress-Reduction (MBSR) program on the physical and emotional health and well-being of adults ages 65 and older.
The effects MBSR may have on the immune system is investigated, including how these effects relate to factors such as perceived health, psychological well-being, age, personality, and mood.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY IgG Anti-KLH Antibody Response Post-treatment |
0.172; 0.104 | .007 sig |
| PRIMARY Trail Making Test |
1.75; 2.01 | .04 sig |
| PRIMARY Electroencephalography Measurement |
0.067; -0.25 | .03 sig |
Eligibility Criteria
Inclusion Criteria
- Age 65 or older
- English speaking
- If prescribed antidepressant or anxiolytic medications, must have maintained a stable regimen for eight weeks prior to enrolling
Exclusion Criteria
- receiving immunosuppressive therapy for cancer or other diseases
- major, uncorrected sensory impairments
- cognitive deficits (MMSE <25, or deficits deemed significant enough to interfere)
- history of a psychotic disorder, bipolar disorder, organic brain syndrome, or mental retardation
- alcohol or substance abuse within the previous year
- severe cardiovascular disease
- known allergies to shellfish
Data sourced from ClinicalTrials.gov (NCT01027780). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.