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N/A N=208 Randomized Treatment

Mindfulness to Improve Elders' Immune and Health Status

Stress, Psychologic

Enrolled (actual)
208
Serious AEs
0.0%
Results posted
Aug 2014
Primary outcome: Primary: IgG Anti-KLH Antibody Response Post-treatment — 0.172; 0.104 OD 405 nm — p=.007

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Mindfulness-Based Stress Reduction (Behavioral)
Age
Older Adult · 65+ yrs
Sex
All
Sponsor
University of Rochester
Primary completion
May 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
IgG Anti-KLH Antibody Response Post-treatment
0.172; 0.104 .007 sig
PRIMARY
Trail Making Test
1.75; 2.01 .04 sig
PRIMARY
Electroencephalography Measurement
0.067; -0.25 .03 sig

Summary

The purpose of the study is to better understand effects of the Mindfulness-Based Stress-Reduction (MBSR) program on the physical and emotional health and well-being of adults ages 65 and older. The effects MBSR may have on the immune system is investigated, including how these effects relate to factors such as perceived health, psychological well-being, age, personality, and mood.

Eligibility Criteria

Inclusion Criteria

  • Age 65 or older
  • English speaking
  • If prescribed antidepressant or anxiolytic medications, must have maintained a stable regimen for eight weeks prior to enrolling

Exclusion Criteria

  • receiving immunosuppressive therapy for cancer or other diseases
  • major, uncorrected sensory impairments
  • cognitive deficits (MMSE <25, or deficits deemed significant enough to interfere)
  • history of a psychotic disorder, bipolar disorder, organic brain syndrome, or mental retardation
  • alcohol or substance abuse within the previous year
  • severe cardiovascular disease
  • known allergies to shellfish
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01027780). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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