N/A N=170 Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Acute Psychological Stress
Primary: Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline) — 0.265; 0.287 mL/(kg·min)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=53 Stress in Inflammatory Bowel Disease
Inflammatory Bowel Diseases · Psychological
Primary: Retention Rate — 23; 25; 19; 22 Participants
Phase 2 N=121 Stress Management for Patients With Multiple Sclerosis
Multiple Sclerosis
Primary: No.of Gd+ Lesions From Week 8 to Week 24 — 46; 33; 5; 13 participants — p=0.04
N/A N=323 Stress, Salt Excretion, and Nighttime Blood Pressure
Blood Pressure · Psychological Stress
Primary: Ratio of Awake-to-asleep Urinary Sodium Excretion Rate (Aim 1) — 1.4 Ratio of awake-to-asleep — p=0.0032
N/A N=295 Involuntary Childlessness and Stress Management
Infertility
Primary: The Effect of Expressive Writing Intervention on Fertility Related Stress — 17.2; 15.7; 17.4; 17.1 units on a scale — p=<0.05
N/A N=199 Caregiver Self-Management of Stress
Caregiver Distress · Job Stress
Primary: 10-item Kessler Psychological Distress Scale (K10) — 23.38; 23.79 score on a scale — p=0.513
N/A N=97 The Impact of Distress on the IVF Outcome
Infertility
Primary: Clinical Pregnancy Rates — 20; 52 percentage of participants
N/A N=6 Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System
Sedentary Behavior · Cardiovascular Risk Factor · Mental Stress
Primary: Mean Change in Brachial-femoral Pulse Wave Velocity (bfPWV) — -0.26; 0.22 m/s
N/A N=28 Resolving Psychological Stress
Post-Traumatic Stress Disorder · Alcohol Use Disorder
Primary: PTSD Symptoms Using PTSD Checklist-5 (PCL-5) at Baseline and 15 Days — 33.2; 36.6; 31.2; 28.2 units on a scale — p=0.322
N/A N=1,418 Effects of Arousal and Stress in Anxiety
Healthy Volunteers
Primary: Go Correct Hits Followed by Button Press — 90.9; 91.6 Percentage of correct responses
Phase 4 N=84 Stress & Premenstrual Symptoms Study
PMDD · Stress · Mood
Primary: Acoustic Startle Response (ASR) Magnitude Based on Menstrual Cycle Phase — 54.2; 53.7; 56.4; 53.3 t score — p=0.139
N/A N=17 Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline
Middle-aged Adults · Major Depressive Disorder
Primary: Nitric Oxide (NO)-Mediated Endothelium-dependent Dilation (EDD) — 70; 74 percentage — p=>0.05
N/A N=179 Mobile Self-Management Program for Stress Reduction in Young Adults
Stress (Psychology)
Primary: Stress at Week 8 — 19.41; 18.35 score on a scale
N/A N=28 Stress and Hypertension in Dementia Caregivers
Hypertension · Stress, Psychological
Primary: Change in Blood Pressure (Systolic) — 129; 127; 122; 124 mmHg
N/A N=112 The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk
PTSD
Primary: Change From Baseline to Post-Intervention in 24-hour Heart Rate Variability (HRV) Estimated From the Standard Deviation of the Interbeat Interval of Normal Sinus Beats…
N/A N=217 Breathe With Ease: A Unique Approach to Managing Stress (BEAMS)
Asthma
Primary: Symptom-free Days in the Last 14 Days — 11.4; 11.6 days in prior 14d — p=0.93
Phase 2 N=212 Personalized Trials for Stress Management Against Standard of Care
Stress
Primary: Between-Arm Difference in Change in Ecological Momentary Assessment (EMA) of Stress. — -0.50; -0.31 units on a scale — p=.316
Phase 4 N=226 Stress Neuroadaptation in Tobacco Dependence
Nicotine Dependence
Primary: Overall Stressor Reactivity — 25.1; 22.5; 32.3; 16.9 microvolts
N/A N=119 Stress Response in Opioid Use Disorder
Opioid-use Disorder
Primary: Change in Negative Affect — 1.67; 1.25; 3.60 scores on a scale
N/A N=94 Stress and the Sympathetic Nervous System in Adults With Depression
Major Depressive Disorder
Primary: Percent of Days Participants Report Stressors — 36; 40 percent of days
N/A N=72 Biological Response to Brief Psychological Challenge
Acute Inflammatory Response to Psychological Stress
Primary: Cell-free Mitochondrial DNA — 165.79; 405.56; 175.45; 164.45 Copies per uL — p=0.86
Phase 2 N=43 Family-Focused, Stress-Reduction Program to Improve the Health Care of Urban Children With Asthma
Asthma
Primary: Mean Score on the Family Asthma Management System Scale (FAMSS) — 4.9; 4.1 units on a scale — p=0.23
Phase 2 N=241 Psychological Influences on Postoperative Recovery
Care, Postoperative · Pain, Postoperative · Surgical Procedures, Operative
Primary: Modified Yale Preoperative Anxiety Scale — 41.59; 37.44; 46.17; 33.65 Score on mYPAS scale — p=.02
N/A N=300 Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process
Chronic Fatigue Syndrome
Primary: Changes in Frequency and Severity of CDC-based CFS Symptoms — 0.29; 0.12; 0.49; 0.05 Units on a scale
N/A N=606 Stress, Sex, and the Generalization of Fear
Psychological Stress
Primary: Fear-potentiated Startle Responses to the CS+ and CS- During Acquisition — 52.059; 19.162; 44.388; 9.732 Fear-potentiated startle (microvolts) — p=0.453
N/A N=23 Stress and the Nervous System
Autonomic Nervous System · Baroreflex · Stress, Physiological
Primary: Cardiovagal Baroreflex Sensitivity (Modified Oxford Technique) — 17.75; 16.90; 14.42; 17.27 ms/mmHg
N/A N=120 College Student Stress: Transitions Over Time
Depressive Symptoms
Primary: Percentage of Eligible Participants Who Agreed to Participate in the Trial — 120 Participants
N/A N=150 Psychological Impact of Pregnancy of Unknown Location
Pregnancy of Unknown Location · Ectopic Pregnancy · Anxiety
Primary: Psychological Morbidity — 10; 10; 5; 5 score on a scale
N/A N=4,412 Healthy Mind Healthy You: A Study of Mindfulness
Stress
Primary: Estimated Weekly Change on World Health Organization-5 (WHO-5) — 0.78; 0.76; 0.41; 0.33 estimated weekly change in scale score — p=.820
N/A N=77 Stress, Emotion Regulation, and Alcohol in Women Veterans
Alcohol Use Disorder · Post Traumatic Stress Disorder
Primary: Change in Alcohol Craving During Experimental Sessions — 2.87; 2.97; 3.18; 3.22 Units on a Scale — p=.94