Phase 2
N=110
Ultrasound Guided Aspiration of Hydrosalpingeal Fluid and IVF-ET Outcomes
Infertility
Bottom Line
View on ClinicalTrials.gov: NCT01040351 ↗Enrolled (actual)
110
Serious AEs
0.0%
Results posted
Aug 2011
Primary outcome: Primary: The Number of Participants Who Achieved Clinical Pregnancy in a Transfer Cycle — 17; 7 participents — p=0.023
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- ultrasound guided aspiration of hydrosalpingeal fluid (Procedure)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Cairo University
- Primary completion
- Feb 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Number of Participants Who Achieved Clinical Pregnancy in a Transfer Cycle |
17; 7 | 0.023 sig |
| SECONDARY The Number of Participants Who Achieved Ongoing Pregnancy in a Transfer Cycle . |
15; 5 | — |
Summary
The aim of this study is to determine whether the ultrasound guided aspiration of hydrosalpingeal fluid at the time of oocyte retrieval can improve the outcomes of IVF-ET .
Eligibility Criteria
Inclusion Criteria
- Patients with unilateral or bilateral hydrosalpinges visible by ultrasound
- Age between 18 - 37 years
- Period of infertility > 1 year
- Body mass index between 19-29
- Normal basal luteinizing hormone (LH), follicle stimulating hormone (FSH) and prolactin concentrations
- Normal recent semen analysis (according to World Health Organization criteria)
Exclusion Criteria
- Uterine fibroid requiring surgical removal
- Endometriosis
- Male factor of infertility requiring ICSI
- Previous IVF cycles
- History of recurrent miscarriage
- Endocrinologic disorders
- Presence of systemic disease contraindicating pregnancy
Data sourced from ClinicalTrials.gov (NCT01040351). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.