N/A
Completed N=283
Polyunsaturated Fatty Acids (PUFA) Status and Cognitive Function in Healthy Young Adults
Attention · Memory · Mood Disorders · Mental Fatigue
Source: ClinicalTrials.gov NCT01075958 ↗
Enrolled (actual)
283
Serious AEs
0.0%
Results posted
Sep 2011
Primary outcomePrimary: Simple Reaction Time (Attention) — 287.7 ms
Summary
To date, the relationship between omega-3 polyunsaturated fatty acids (n-3 PUFAs) in cognitively intact individuals has only been examined in a limited number of studies; it is at present unknown whether supplementation with n-3 PUFAs can improve cognitive function and mood in this population. Further to this, it still remains to be established whether a relationship exists between peripheral fatty acid status-reflective of dietary n-3 PUFA intake-and cognitive function in this population. The current study therefore aims to address this issue by exploring the relationship between serum PUFAs and specific cognitive functions in a sample of healthy adults. To this end, participants will complete a range of cognitive tasks evaluating performance across the domains of attention, memory and executive function. Self-report mood assessments will be included as secondary measures.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Simple Reaction Time (Attention) |
287.7 | — |
| PRIMARY Choice Reaction Time (Attention) |
412.79 | — |
| PRIMARY Four Choice Reaction Time (Attention) |
499.52 | — |
| PRIMARY Numeric Working Memory (Working Memory) |
95.57 | — |
| PRIMARY Alphabetic Working Memory (Working Memory) |
94.5 | — |
| PRIMARY Corsi Blocks Span (Spatial Working Memory) |
5.90 | — |
| PRIMARY 3-back Task (Working Memory) |
80.89 | — |
| PRIMARY Immediate Word Recall (Episodic Memory) |
6.21 | — |
| PRIMARY Delayed Word Recall (Episodic Memory) |
4.73 | — |
| PRIMARY Word Recognition (Episodic Memory) |
80.35 | — |
| SECONDARY Depression, Anxiety and Stress Scale (DASS) |
22.45 | — |
Eligibility Criteria
Inclusion Criteria
- Male/Female
- 18-35 years
- Healthy
- No herbal supplements/prescription medications (excl. contraceptive pill)
- Non smoker
- Native English speaker
Exclusion Criteria
- BMI ≥ 30
Data sourced from ClinicalTrials.gov (NCT01075958). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.